SPTSSB: A Potential Drug Target and Biomarker (G165679)

Target Name: SPTSSB

NCBI ID: G165679

SPTSSB

SPTSSB: A Potential Drug Target and Biomarker

Spermidine-modified transmembrane spermine synthase (SPTSSB) is a protein that is expressed in various tissues and cells in the human body. It is a key enzyme in the spermatozoa, which are responsible for the production of sperm cells. SPTSSB has been identified as a potential drug target and biomarker due to its unique structure and its involvement in several biological processes.

SPTSSB is a protein that is composed of 218 amino acids. It is expressed in the testes, brain, heart, and other tissues in the body. It is primarily localized to the endoplasmic reticulum (ER), a structure that is responsible for the storage and transport of proteins in the cells. SPTSSB is also known as SMY1 (spermidine-modified transmembrane spermine synthase), which is a subunit of the enzyme SMY2.

SPTSSB is involved in several important biological processes in the body, including the production of sperm cells, cell signaling, and neurotransmission. It is a key enzyme in the spermatozoa, which are responsible for the production of sperm cells. SPTSSB plays a crucial role in the production of spermatozoa by regulating the structure and function of the microtubules that are responsible for transporting the spermatozoa to the testes.

SPTSSB is also involved in cell signaling, which is the process by which cells communicate with each other to coordinate their activities. It is a key regulator of the protein known as tubulin, which is responsible for the structure and stability of microtubules. SPTSSB plays a crucial role in the regulation of tubulin, which is a critical protein for the proper functioning of microtubules.

SPTSSB is also involved in neurotransmission, which is the process by which nerve cells communicate with each other to transmit signals. It is a key regulator of the protein known as neurotrophin, which is responsible for the survival and growth of nerve cells. SPTSSB plays a crucial role in the regulation of neurotrophin, which is a critical protein for the proper functioning of nerve cells.

SPTSSB has been identified as a potential drug target due to its unique structure and its involvement in several biological processes. It is a good candidate for small molecule inhibitors, which are drugs that can inhibit the activity of SPTSSB and prevent it from participating in the processes it is involved in.

In conclusion, SPTSSB is a protein that is involved in several important biological processes in the body, including the production of sperm cells, cell signaling, and neurotransmission. It is a potential drug target due to its unique structure and its involvement in several biological processes. Further research is needed to fully understand the role of SPTSSB in the body and its potential as a drug target.

Protein Name: Serine Palmitoyltransferase Small Subunit B

Functions: Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference, complexes with this subunit showing a clear preference for longer acyl-CoAs. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference. May play a role in signal transduction

The "SPTSSB Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPTSSB comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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