SQOR: A Key Regulator of Sodium and Glucose Transport (G58472)

Target Name: SQOR

NCBI ID: G58472

SQOR

SQOR: A Key Regulator of Sodium and Glucose Transport

SQOR (Sodium-Glucose cotransporter Regulatory protein) is a protein that is expressed in most tissues and cells in the body. It is a key regulator of the transport of sodium and glucose across the cell membrane and is involved in the regulation of a variety of physiological processes, including blood pressure, water balance, and the delivery of nutrients into cells.

SQOR is a member of the T-cell superfamily and is characterized by its transmembrane domain and a cytoplasmic tail. It is expressed in a variety of tissues, including the brain, heart, kidneys, and endothelial cells. It is also expressed in the placenta and has been shown to be involved in the regulation of pregnancy outcomes.

SQOR functions as a transporter for the sodium and glucose across the cell membrane. This is accomplished through its unique structure, which consists of a long cytoplasmic tail that is involved in the formation of a transmembrane complex with the cell membrane. This structure allows SQOR to interact with a variety of different molecules, including sodium and glucose transport proteins.

SQOR is involved in the regulation of a variety of physiological processes, including blood pressure, water balance, and the delivery of nutrients into cells. For example, it is known to be involved in the regulation of sodium intake and excretion, which is important for maintaining the proper balance of sodium in the body. It is also involved in the regulation of water intake and output, which is important for maintaining the proper balance of water in the body.

In addition to its role in regulating sodium and water intake, SQOR is also involved in the delivery of nutrients into cells. This is accomplished through its role as a transporter for a variety of different nutrients, including glucose, which is a critical source of energy for the body.

SQOR is also involved in the regulation of inflammation and immune responses. This is accomplished through its role as a regulator of the production and function of natural killer cells, which are important for fighting off infections and diseases.

SQOR is a drug target that is being studied for a variety of potential therapeutic applications. For example, SQOR has been shown to be a potential therapeutic target for the treatment of hypertension, heart failure, and other cardiovascular conditions. Studies have also shown that SQOR is involved in the regulation of pregnancy outcomes and that it may be a useful target for the treatment of infertility.

Overall, SQOR is a protein that is involved in a variety of important physiological processes in the body. Its unique structure and function make it an attractive target for research and potential therapeutic applications. Further studies are needed to fully understand the role of SQOR in the regulation of physiological processes and to determine its potential as a drug target.

Protein Name: Sulfide Quinone Oxidoreductase

Functions: Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone-10, giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron acceptor; can use sulfite, sulfide or cyanide (in vitro) (PubMed:22852582). It is believed the in vivo electron acceptor is glutathione (PubMed:25225291, PubMed:29715001)

The "SQOR Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SQOR comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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