Target Name: DHRS7C
NCBI ID: G201140
Review Report on DHRS7C Target / Biomarker Content of Review Report on DHRS7C Target / Biomarker
DHRS7C
Other Name(s): Dehydrogenase/reductase 7C, transcript variant 2 | DRS7C_HUMAN | Protein SDR32C2 | Short-chain dehydrogenase/reductase family 32C member 2 | dehydrogenase/reductase (SDR family) member 7C | short-chain dehydrogenase/reductase family 32C member 2 | DHRS7C variant 1 | Dehydrogenase/reductase SDR family member 7C (isoform 1) | SDR32C2 | Dehydrogenase/reductase (SDR family) member 7C | sarcoplasmic reticulum protein of 35 kDa | Short chain dehydrogenase/reductase family 32C, member 2 | Protein SRP-35 | dehydrogenase/reductase 7C | Dehydrogenase/reductase SDR family member 7C (isoform 2) | Dehydrogenase/reductase 7C, transcript variant 1 | DHRS7C variant 2 | Dehydrogenase/reductase SDR family member 7C

DHRS7C Gene Encodes Protein Involved in Detoxification, Energy Production and Cellular Growth

DHRS7C (Dehydrogenase/reductase 7C) is a gene that encodes a protein known as DHRS7C in humans. The protein produced by this gene is involved in a variety of cellular processes within the body. One of the main functions of DHRS7C is to participate in the detoxification process, which is essential for the survival of all living organisms. DHRS7C is also involved in the production of energy, as well as in the regulation of cellular growth and differentiation.

Transcript variants are a common occurrence in the gene pool of any protein-coding gene. These variants can result from a variety of genetic mechanisms, such as point mutations, insertions, deletions, and rearrangements. DHRS7C has several transcript variants, including transcript variant 2.

Transcript variant 2 is a common variant of DHRS7C and is associated with the production of a protein with a molecular weight of approximately 41 kDa. This protein is known as DHRS7C-GFP and is expressed in a variety of cell types, including neurons, muscle cells, and blood cells. DHRS7C-GFP is involved in a variety of cellular processes, including the detoxification of harmful substances, the production of energy, and the regulation of cellular growth and differentiation.

DHRS7C-GFP is also shown to play a role in the development and progression of certain diseases, such as cancer. Studies have shown that high levels of DHRS7C-GFP are associated with the development of various types of cancer, including breast, ovarian, and prostate cancer. Additionally, DHRS7C-GFP has also been shown to be involved in the regulation of cellular angiogenesis, which is the process by which new blood vessels are formed in the body. This may be a potential drug target for diseases that involve the regulation of angiogenesis.

In addition to its role in the detoxification process and cellular angiogenesis, DHRS7C is also involved in the production of energy. This is accomplished through a process called cellular respiration, which is the process by which cells produce the energy they need to function. DHRS7C is a key enzyme in this process and is involved in the production of ATP, which is the primary source of energy for the cell.

Another function of DHRS7C is the regulation of cellular growth and differentiation. This is accomplished through the regulation of cell proliferation and the production of cell-specific proteins. DHRS7C is involved in the regulation of cell division and in the production of proteins that are involved in cell signaling and differentiation.

In conclusion, DHRS7C is a gene that encodes a protein that is involved in a variety of cellular processes within the body. DHRS7C-GFP is a transcript variant of DHRS7C that is associated with the production of a protein that is involved in the detoxification process, energy production, and cellular growth and differentiation. Further research is needed to fully understand the role of DHRS7C-GFP in the development and progression of various diseases. It may be a potential drug target or biomarker in the future.

Protein Name: Dehydrogenase/reductase 7C

Functions: NADH-dependent oxidoreductase which catalyzes the oxidation of all-trans-retinol to all-trans-retinal. Plays a role in the regulation of cardiac and skeletal muscle metabolic functions. Maintains Ca(2+) intracellular homeostasis by repressing Ca(2+) release from the sarcoplasmic reticulum (SR) in myotubes, possibly through local alternations in NAD/NADH or retinol/retinal. Also plays a role in Ca(2+) homeostasis by controlling Ca(2+) overload in the cytosol and the SR in myotubes. Involved in glucose uptake into skeletal muscles and muscle performance by activating PI3K and mTORC2-mediated AKT1 phosphorylation signaling pathways, possibly through the action of its downstream catalytic product all-trans-retinoic acid

The "DHRS7C Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DHRS7C comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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