CCDC83: A Potential Drug Target and Biomarker (G220047)

Target Name: CCDC83

NCBI ID: G220047

CCDC83

CCDC83: A Potential Drug Target and Biomarker

CDC83, also known as coiled-coil domain containing 83, is a protein that is expressed in various tissues of the human body. It is a member of the superfamily of coiled-coil proteins, which are a type of protein that can form helices and are involved in various cellular processes. One of the functions of CDC83 is to regulate the assembly and disassembly of other proteins, which is essential for proper cellular function.

CDC83 has also been shown to play a role in the development and progression of various diseases, including cancer. Its involvement in these processes makes it an attractive drug target and a potential biomarker for certain diseases. In this article, we will discuss the potential drug target and biomarker properties of CDC83, as well as its current status as a drug target and its potential as a biomarker for certain diseases.

Potential Drug Target

CDC83 has been shown to be involved in the regulation of cellular processes that are important for the development and progression of various diseases, including cancer. One of the known functions of CDC83 is to regulate the assembly and disassembly of other proteins, which is essential for proper cellular function.

Studies have shown that CDC83 can interact with various proteins, including the protein p16INK4a. p16INK4a is a tumor suppressor protein that plays a role in the regulation of cell growth and division. When p16INK4a is expressed in cells, it can inhibit the growth and spread of cancer cells. However, when p16INK4a is inhibited, cancer cells can continue to grow and spread.

CDC83 has been shown to play a role in the regulation of p16INK4a stability and function. Studies have shown that when CDC83 is expressed in cells, it can physically interact with p16INK4a and enhance its stability. This interaction between CDC83 and p16INK4a has the potential to contribute to the development and progression of cancer.

In addition to its role in regulating p16INK4a stability, CDC83 has also been shown to play a role in the regulation of other proteins that are involved in the development and progression of cancer. For example, studies have shown that CDC83 can interact with the protein T-cell receptor (TCR), which is involved in the regulation of immune responses. This interaction between CDC83 and TCR has the potential to contribute to the development and progression of cancer in immune-depressed individuals.

Potential Biomarker

CDC83 has also been shown to serve as a potential biomarker for certain diseases. Its involvement in the regulation of cellular processes that are important for the development and progression of diseases makes it an attractive candidate for use as a biomarker.

Studies have shown that CDC83 can be used as a biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. For example, studies have shown that CDC83 can be used as a biomarker for cancer by regulating the assembly and disassembly of other proteins, which is essential for the development and progression of cancer.

In addition to its potential as a cancer biomarker, CDC83 has also been shown to be involved in the regulation of other proteins that are involved in the development and progression of neurodegenerative diseases. For example, studies have shown that CDC83 can interact with the protein huntingtin-1 (HING), which is involved in the regulation of neural stem cell proliferation and differentiation. This interaction between CDC83 and HING has the potential to contribute to the development and progression of neurodegenerative diseases.

Current Status as a

Protein Name: Coiled-coil Domain Containing 83

The "CCDC83 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CCDC83 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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