TALDO1: A Negative Regulator of TAL1 and A Key Player in Cellular Signaling

Target Name: TALDO1

NCBI ID: G6888

TALDO1

TALDO1: A Negative Regulator of TAL1 and A Key Player in Cellular Signaling

TALDO1 (TALinding-controlled receptor-one) is a protein that is expressed in various tissues and cells throughout the body. It is a member of the TAL family of proteins, which are known for their role in intracellular signaling. TALDO1 is unique because it is a negative regulator of the TAL1 gene, which encodes the protein TAL1.

The TAL1 gene is a key regulator of cell growth and differentiation, and it is involved in the development and maintenance of tissues such as the brain, spinal cord, and heart. TAL1 is a transcription factor that activates target genes by binding to their DNA, and it is involved in the regulation of a wide range of cellular processes, including cell growth, apoptosis (programmed cell death), and inflammation.

TALDO1 is a 21-kDa protein that is composed of 115 amino acid residues. It has a unique structure that is composed of a catalytic domain, a transmembrane region, and an intracellular tail. The catalytic domain is the region of the protein that contains the amino acids that are involved in the catalytic activity of TALDO1. This domain is known for its ability to catalyze the transfer of a phosphate group from an ATP molecule to a protein substrate, which is a key step in the regulation of cellular processes.

The transmembrane region is the region of the protein that spans the membrane of the cell and is involved in the regulation of the cell's surface. This region is known for its ability to interact with other proteins and molecules that are located on the cell's surface.

The intracellular tail is the region of the protein that extends from the transmembrane region and interacts with other proteins and molecules within the cell. This region is known for its ability to interact with the protein tyrosine kinase (TK), which is a key regulator of cell growth and differentiation.

TALDO1 is involved in a wide range of cellular processes, including the regulation of cell growth, apoptosis, and inflammation. It is a negative regulator of the TAL1 gene, which means that it works to inhibit the activity of TAL1. This helps to ensure that the cell does not undergo rapid growth and division, which can lead to the formation of cancerous cells.

TALDO1 is also involved in the regulation of the stress response. When the cell experiences stress, TALDO1 helps to ensure that the cell responds in a controlled and coordinated manner. This is important for the survival of the cell and for the proper functioning of the organism.

In addition to its role in the regulation of cell growth and stress response, TALDO1 is also involved in the regulation of the immune response. It is a critical regulator of the T-cell receptor (TCR), which is responsible for the recognition of foreign substances in the body. TALDO1 helps to ensure that the T-cells are able to recognize and respond to foreign substances in a timely and effective manner.

TALDO1 is also involved in the regulation of the blood-brain barrier. The blood-brain barrier is a barrier that separates the brain from the bloodstream, and it is responsible for the delivery of nutrients and oxygen to the brain. regulation of the blood-brain barrier, which allows certain nutrients and oxygen to enter the brain while keeping others out.

In conclusion, TALDO1 is a unique protein that is involved in a wide range of cellular processes. Its role in the regulation of cell growth and stress response, as well as its involvement in the regulation of the immune and blood-brain barrier, make it an attractive potential drug target or biomarker. Further research is needed to fully understand the mechanisms of TALDO1's function in these processes and to develop effective treatments for the

Protein Name: Transaldolase 1

Functions: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate (PubMed:8955144, PubMed:18687684). Not only acts as a pentose phosphate pathway enzyme, but also affects other metabolite pathways by altering its subcellular localization between the nucleus and the cytoplasm (By similarity)

The "TALDO1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TALDO1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets