Target Name: TACR3
NCBI ID: G6870
Review Report on TACR3 Target / Biomarker Content of Review Report on TACR3 Target / Biomarker
TACR3
Other Name(s): TAC3R | HH11 | neurokinin beta receptor | NK3R_HUMAN | NK-3R | Tachykinin NK3 receptor | tachykinin receptor 3 | neurokinin B receptor | NK3 | NK3 receptor | NKR | NK-3 receptor | Neuromedin-K receptor | Neurokinin B receptor | Tachykinin receptor 3 | NK3R | TAC3RL

TACR3: A Protein Involved in The Immune Response

TACR3 (TAC3R) is a protein that is expressed in various tissues of the body, including the brain, heart, lungs, and kidneys. It is a member of the T-cell antigen receptor (TCR) family, which is a type of protein that is expressed in the immune system to recognize and respond to foreign substances in the body.

The TACR3 protein is composed of four distinct domains: an N-terminus, a transmembrane segment, a cytoplasmic tail, and a C-terminus. The N-terminus of TACR3 is a 24 amino acid residue that contains a nucleotide sequence that is similar to that of the T-cell antigen receptor alpha chain (TCR伪). The transmembrane segment is a 50 amino acid residue that spans the entire cell membrane and is involved in the formation of the T-cell receptor complex. The cytoplasmic tail is a 20 amino acid residue that extends from the cytoplasm of the T-cell and is involved in the maintenance of the T-cell receptor complex. The C-terminus is a 24 amino acid residue that is located in the cytoplasm and is involved in the recognition of foreign substances by the T-cell receptor.

TACR3 is a critical protein that is involved in the immune response. It is expressed in a variety of tissues, including the brain, heart, lungs, and kidneys, and is involved in the development and maintenance of the immune system.

One of the functions of TACR3 is to recognize foreign substances in the body and initiate an immune response. When a foreign substance binds to TACR3, it triggers the activation of the immune system and the production of antibodies. These antibodies are designed to recognize and neutralize the foreign substance, and they are released into the bloodstream to protect the body against infection.

Another function of TACR3 is to regulate the activity of the immune system. TACR3 is involved in the regulation of the activation and proliferation of T-cells, as well as the regulation of the production of antibodies. It is also involved in the regulation of the release of T-cells from the body, which is important for maintaining immune tolerance and avoiding the production of autoimmune diseases.

TACR3 is also involved in the regulation of cellular signaling processes. It is involved in the regulation of the signaling processes that occur between T-cells and other immune cells, as well as the regulation of the signaling processes that occur between T-cells and the brain. This involvement in cellular signaling processes is important for the regulation of the immune response and the maintenance of immune tolerance.

In conclusion, TACR3 is a critical protein that is involved in the immune response and cellular signaling processes. It is expressed in various tissues of the body and is involved in the development and maintenance of the immune system. Further research is needed to better understand the role of TACR3 in the immune response and to develop effective treatments for T-cell disorders.

Protein Name: Tachykinin Receptor 3

Functions: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P

The "TACR3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TACR3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TACSTD2 | TADA1 | TADA2A | TADA2B | TADA3 | TAF1 | TAF10 | TAF11 | TAF11L2 | TAF11L3 | TAF12 | TAF12-DT | TAF13 | TAF15 | TAF1A | TAF1A-AS1 | TAF1B | TAF1C | TAF1D | TAF1L | TAF2 | TAF3 | TAF4 | TAF4B | TAF5 | TAF5L | TAF5LP1 | TAF6 | TAF6L | TAF7 | TAF7L | TAF8 | TAF9 | TAF9B | TAFA1 | TAFA2 | TAFA3 | TAFA4 | TAFA5 | TAFAZZIN | TAGAP | TAGAP-AS1 | TAGLN | TAGLN2 | TAGLN3 | TAK1 | TAL1 | TAL2 | TALDO1 | TAM Receptor tyrosine kinase | TAMALIN | TAMM41 | TANC1 | TANC2 | TANGO2 | TANGO6 | TANK | Tankyrase | TAOK1 | TAOK2 | TAOK3 | TAP1 | TAP2 | TAPBP | TAPBPL | TAPT1 | TAPT1-AS1 | TARBP1 | TARBP2 | TARDBP | TARDBPP1 | TARDBPP3 | TARID | TARM1 | TARP | TARS1 | TARS2 | TARS3 | TAS1R1 | TAS1R2 | TAS1R3 | TAS2R1 | TAS2R10 | TAS2R13 | TAS2R14 | TAS2R16 | TAS2R19 | TAS2R20 | TAS2R3 | TAS2R30 | TAS2R31 | TAS2R38 | TAS2R39 | TAS2R4 | TAS2R40 | TAS2R41 | TAS2R42 | TAS2R43 | TAS2R45 | TAS2R46