Target Name: TAFA4
NCBI ID: G151647
Review Report on TAFA4 Target / Biomarker Content of Review Report on TAFA4 Target / Biomarker
TAFA4
Other Name(s): TAFA4 variant 1 | Protein FAM19A4 | family with sequence similarity 19 member A4, C-C motif chemokine like | TAFA4_HUMAN | TAFA-4 | TAFA chemokine like family member 4 | family with sequence similarity 19 (chemokine (C-C motif)-like), member A4 | Chemokine-like protein TAFA-4 | TAFA chemokine like family member 4, transcript variant 1 | FLJ25161 | protein FAM19A4 | FAM19A4

TAFA4: A Promising Drug Target and Biomarker for the Treatment of Inflammatory Diseases

Abstract:

Inflammatory diseases such as rheumatoid arthritis, inflammatory bowel disease, and chronic obstructive pulmonary disease (COPD) have a significant impact on public health, causing significant morbidity and mortality. TheTAFA4 gene, located on chromosome 16, has been identified as a potential drug target and biomarker for the treatment of inflammatory diseases. This article will review the current research onTAFA4 and its potential as a drug target and biomarker in inflammatory diseases.

Introduction:

Inflammatory diseases are a leading cause of morbidity and mortality worldwide, including rheumatoid arthritis, inflammatory bowel disease, and COPD. These diseases cause significant pain, discomfort, and disability, and can also lead to significant economic burden due to lost productivity and healthcare costs. TheTAFA4 gene, located on chromosome 16, has been identified as a potential drug target and biomarker for the treatment of inflammatory diseases.

TheTAFA4 gene:

TheTAFA4 is a gene that encodes for a protein known as TAF4, which plays a critical role in the immune response and inflammation. TAF4 is a cytoplasmic protein that is involved in the regulation of T cell development, activation, and function. It is also involved in the regulation of inflammation, cell death, and autophagy. TheTAFA4 gene has been identified as a potential drug target and biomarker for the treatment of inflammatory diseases due to its unique function in the immune response and inflammation.

Potential drug targets:

TAFA4 is involved in the regulation of multiple immune and inflammatory processes, making it a potential drug target for the treatment of inflammatory diseases. Several studies have identified potential drug targets within the TAF4 gene.

1. TheTAFA4 signaling pathway:

TheTAFA4 is involved in the regulation of T cell development, activation, and function, which are critical for the immune response. TheTAFA4 has been shown to regulate the development and function of T cells, which play a critical role in the immune response and inflammation.

1. TheTAFA4-mediated inflammation:

TAFA4 is involved in the regulation of inflammation, cell death, and autophagy. It has been shown to play a critical role in the regulation of pro-inflammatory responses and to promote anti-inflammatory responses.

1. TheTAFA4-mediated cell death:

TAFA4 is involved in the regulation of cell death, which is a critical process in the immune response and inflammation. It has been shown to play a critical role in the regulation of apoptosis, which is a natural mechanism of cell death that helps to eliminate damaged or dysfunctional cells.

1. TheTAFA4-mediated autophagy:

TAFA4 is involved in the regulation of autophagy, which is a critical process in the immune response and inflammation. It has been shown to play a critical role in the regulation of autophagy, which is the process by which cells break down and recycle damaged or dysfunctional cells.

Potential biomarkers:

TAFA4 has also been identified as a potential biomarker for the treatment of inflammatory diseases. Several studies have shown that TAF4 levels are elevated in individuals with inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease.

Conclusion:

TAFA4 is a gene that encodes for a protein involved in the immune response and inflammation. TheTAFA4 has been identified as a potential drug target and biomarker for the treatment of inflammatory diseases due to its unique function in the immune response and inflammation. Further research is needed to

Protein Name: TAFA Chemokine Like Family Member 4

Functions: Modulates injury-induced and chemical pain hypersensitivity (By similarity). Ligand of FPR1, can chemoattract macrophages, promote phagocytosis and increase ROS release (PubMed:25109685)

The "TAFA4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TAFA4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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TAFA5 | TAFAZZIN | TAGAP | TAGAP-AS1 | TAGLN | TAGLN2 | TAGLN3 | TAK1 | TAL1 | TAL2 | TALDO1 | TAM Receptor tyrosine kinase | TAMALIN | TAMM41 | TANC1 | TANC2 | TANGO2 | TANGO6 | TANK | Tankyrase | TAOK1 | TAOK2 | TAOK3 | TAP1 | TAP2 | TAPBP | TAPBPL | TAPT1 | TAPT1-AS1 | TARBP1 | TARBP2 | TARDBP | TARDBPP1 | TARDBPP3 | TARID | TARM1 | TARP | TARS1 | TARS2 | TARS3 | TAS1R1 | TAS1R2 | TAS1R3 | TAS2R1 | TAS2R10 | TAS2R13 | TAS2R14 | TAS2R16 | TAS2R19 | TAS2R20 | TAS2R3 | TAS2R30 | TAS2R31 | TAS2R38 | TAS2R39 | TAS2R4 | TAS2R40 | TAS2R41 | TAS2R42 | TAS2R43 | TAS2R45 | TAS2R46 | TAS2R5 | TAS2R50 | TAS2R60 | TAS2R63P | TAS2R64P | TAS2R7 | TAS2R8 | TAS2R9 | TASL | TASOR | TASOR2 | TASP1 | Taste receptor type 2 | Taste Receptors Type 1 | TAT | TAT-AS1 | TATDN1 | TATDN2 | TATDN2P3 | TATDN3 | TAX1BP1 | TAX1BP3 | TBATA | TBC1D1 | TBC1D10A | TBC1D10B | TBC1D10C | TBC1D12 | TBC1D13 | TBC1D14 | TBC1D15 | TBC1D16 | TBC1D17 | TBC1D19 | TBC1D2 | TBC1D20 | TBC1D21 | TBC1D22A