ATP6V0D2: Key Protein of The V-ATPase Complex (G245972)

Target Name: ATP6V0D2

NCBI ID: G245972

ATP6V0D2

ATP6V0D2: Key Protein of The V-ATPase Complex

ATP6V0D2, also known as V-ATPase subunit d 2, is a protein that plays a crucial role in the function of the V-ATPase complex in eukaryotic cells. The V-ATPase is a transmembrane protein that is involved in the regulation of various cellular processes, including intracellular signaling, cell survival, and transport. The subunit d 2 of the V-ATPase complex is a 21-kDa protein that is composed of 125 amino acid residues.

The V-ATPase complex is a protein-protein interaction domain that consists of six transmembrane proteins: ATP6V0D1 (also known as V-ATPase subunit a 1), ATP6V0D2, ATP6V0D3, ATP6V0D4, ATP6V0D5, and ATP6V0D6. These proteins form a monomeric complex that is responsible for generating ATP fromADP using a high-energy ATP synthase. The V-ATPase is involved in various cellular processes, including the regulation of cell growth, differentiation, and survival.

ATP6V0D2 is a key protein of the V-ATPase complex because it plays a crucial role in the regulation of the activity of the complex. The protein is involved in the regulation of the ATPase activity by interacting with the ATP-binding site on the V-ATPase subunit a 1. The interaction between ATP6V0D2 and the ATP-binding site is critical for the regulation of the ATPase activity.

ATP6V0D2 is also involved in the regulation of the release of ATP from the V-ATPase complex. The protein is involved in the regulation of the release of ATP from the complex by interacting with the release site on the V-ATPase subunit d 3. The interaction between ATP6V0D2 and the release site is critical for the regulation of the release of ATP from the V-ATPase complex.

In addition to its role in the regulation of ATPase activity and release, ATP6V0D2 is also involved in the regulation of cellular processes that are independent of the V-ATPase complex. The protein is involved in the regulation of cell adhesion, migration, and the regulation of the cytoskeleton.

ATP6V0D2 is a potential drug target and biomarker because of its involvement in the regulation of various cellular processes. The protein is a good candidate for targeting with small molecules or antibodies because of its unique structure and the various functions that it plays in the cell.

In conclusion, ATP6V0D2 is a protein that plays a crucial role in the regulation of various cellular processes, including the regulation of ATPase activity and release, cell adhesion, migration, and the regulation of the cytoskeleton. The protein is involved in the regulation of cellular processes that are independent of the V-ATPase complex and is a potential drug target and biomarker. Further research is needed to fully understand the role of ATP6V0D2 in the regulation of cellular processes and its potential as a drug target.

Protein Name: ATPase H+ Transporting V0 Subunit D2

Functions: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). May play a role in coupling of proton transport and ATP hydrolysis (By similarity). Regulator of osteoclast fusion and bone formation (By similarity)

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