GABRA4: A Protein Involved in Neuronal Communication and Synaptic Plasticity

Target Name: GABRA4

NCBI ID: G2557

GABRA4

Other Name(s): gamma-aminobutyric acid type A receptor subunit alpha4 | Gamma-aminobutyric-acid receptor alpha 4 subunit | Gamma-aminobutyric acid type A receptor subunit alpha4, transcript variant 1 | gamma-aminobutyric acid A receptor alpha 4 | gamma-aminobutyric acid type A receptor alpha4 subunit | gamma-aminobutyric acid (GABA) A receptor, alpha 4 | GBRA4_HUMAN | GABRA4 variant 1 | Gamma-aminobutyric acid receptor subunit alpha-4 | GABA(A) receptor subunit alpha-4 | Gamma-aminobutyric acid receptor subunit alpha-4 (isoform 1) | GABA(A) receptor, alpha 4

GABRA4: A Protein Involved in Neuronal Communication and Synaptic Plasticity

GABRA4 is a protein that is expressed in many different tissues throughout the body. It is a subunit of the gamma-aminobutyric acid (GABA) receptor, which is a neurotransmitter that plays a crucial role in the regulation of neural circuits. The GABA receptor is composed of two subunits: GABA伪1 and GABA伪2. GABA伪1 is the primary receptor, while GABA伪2 is a ligand receptor that activates the GABA伪1 receptor.

GABRA4 is a 21-kDa protein that is expressed in the brain, heart, liver, and kidneys. It is primarily localized to the postsynaptic terminal of neurons, where it interacts with the GABA伪2 receptor. GABRA4 is involved in the regulation of a wide range of physiological processes, including neuronal communication, neurotransmitter release, and synaptic plasticity.

One of the key functions of GABRA4 is its role in synaptic plasticity, which is the ability of the nervous system to change and adapt over time. GABRA4 is involved in the regulation of synaptic plasticity by modulating the activity of the GABA伪2 receptor. This can lead to changes in the levels of neurotransmitters, such as dopamine and glutamate, which can in turn affect the strength and stability of synaptic connections.

GABRA4 is also involved in the regulation of pain and anxiety. It has been shown to play a role in the modulation of pain perception and the regulation of anxiety-like behaviors. GABRA4 has been shown to interact with other proteins that are involved in pain and anxiety regulation, including the opioid receptor and the serotonin system.

In addition to its role in synaptic plasticity and pain and anxiety regulation, GABRA4 is also involved in the regulation of sleep. It has been shown to play a role in the regulation of sleep-wake cycles and the control of sleep behavior. GABRA4 has been shown to interact with the clock gene Per2, which is involved in the regulation of sleep-wake cycles.

GABRA4 is also involved in the regulation of cardiovascular function. It has been shown to play a role in the regulation of heart rate and blood pressure, and it is also involved in the regulation of blood vessel diameter. GABRA4 has been shown to interact with the protein PDGF-尾, which is involved in the regulation of cardiovascular function.

GABRA4 is also involved in the regulation of inflammation. It has been shown to play a role in the regulation of inflammation and immune responses. GABRA4 has been shown to interact with the protein NF-kappa-B, which is involved in the regulation of inflammation and immune responses.

GABRA4 is also involved in the regulation of neuroendocrine function. It has been shown to play a role in the regulation of neuroendocrine secretion, including the regulation of thyroid function and the production of insulin. GABRA4 has been shown to interact with the protein TrkB, which is involved in the regulation of neuroendocrine function.

GABRA4 is also involved in the regulation of physical activity. It has been shown to play a role in the regulation of physical activity and energy metabolism. GABRA4 has been shown to interact with the protein p53, which is involved in the regulation of physical activity and energy metabolism.

GABRA4 is also involved in the regulation of social behavior. It has been shown to play a role in the regulation of social behavior, including the modulation of social interaction and the regulation of emotional behavior. GABRA4 has been shown to interact with the protein

Protein Name: Gamma-aminobutyric Acid Type A Receptor Subunit Alpha4

Functions: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel

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