Exploring The Biology and Potential Therapeutic Applications of KANK2

Target Name: KANK2

NCBI ID: G25959

KANK2

Exploring The Biology and Potential Therapeutic Applications of KANK2

KANK2, also known as matrix-remodeling-associated protein 3, is a protein that is expressed in various tissues throughout the body. It is a key player in the regulation of cell structure and function, and is involved in a wide range of cellular processes.

Recent studies have suggested that KANK2 may have potential as a drug target or biomarker. In this article, we will explore the biology and potential therapeutic applications of KANK2.

The biology of KANK2

KANK2 is a member of the K-type ATP-binding proteins, which are a family of transmembrane proteins that play a critical role in cellular signaling. These proteins are characterized by their ability to bind to ATP and regulate various cellular processes, including cell growth, differentiation, and signaling pathways.

KANK2 is expressed in a wide range of tissues, including muscle, heart, liver, and brain. It is involved in the regulation of cellular processes that are critical for normal tissue growth and maintenance, including cell division, cell growth, and cell signaling.

One of the key functions of KANK2 is its role in the regulation of cell division. KANK2 has been shown to play a critical role in the regulation of cell proliferation and has been shown to interact with several key signaling pathways, including the PI3K/Akt signaling pathway.

In addition to its role in cell division, KANK2 is also involved in the regulation of cell signaling. It has been shown to play a critical role in the regulation of several signaling pathways, including the TGF-β signaling pathway.

KANK2's role in disease

The role of KANK2 in disease is still being fully understood, but studies have suggested that it may be involved in a wide range of diseases.

One of the key findings of recent studies is the suggestion that KANK2 may be a potential drug target for several diseases, including cancer. This is because KANK2 has been shown to play a critical role in the regulation of cell growth and signaling, and may be involved in the regulation of tumor growth.

In addition to its potential role as a drug target, KANK2 has also been suggested as a potential biomarker for several diseases. This is because it is expressed in a wide range of tissues and has been shown to play a critical role in the regulation of cellular processes that are important for disease development.

Potential therapeutic applications of KANK2

The potential therapeutic applications of KANK2 are still being explored, but studies have suggested that it may be a useful target for several diseases.

One of the key potential therapeutic applications of KANK2 is its potential as a drug for cancer. Cancer growth is often fueled by the regulation of cell growth and signaling, and KANK2 may be involved in the regulation of these processes. Therefore, KANK2 has been shown to be a potential target for cancer therapies that aim to inhibit cell growth or disrupt signaling pathways.

In addition to its potential as a cancer drug, KANK2 has also been suggested as a potential biomarker for several other diseases. For example, KANK2 has been shown to be involved in the regulation of cellular processes that are important for the development of heart disease, and may be a useful biomarker for heart disease.

Conclusion

KANK2 is a protein that is expressed in various tissues throughout the body and is involved in a wide range of cellular processes. Recent studies have suggested that KANK2 may have potential as a drug target or biomarker for several diseases, including cancer and heart disease. Further research is needed to fully understand the role of KANK2 in disease and to explore its potential therapeutic applications.

Protein Name: KN Motif And Ankyrin Repeat Domains 2

Functions: Involved in transcription regulation by sequestering in the cytoplasm nuclear receptor coactivators such as NCOA1, NCOA2 and NCOA3 (PubMed:17476305). Involved in regulation of caspase-independent apoptosis by sequestering the proapoptotic factor AIFM1 in mitochondria (PubMed:22371500). Pro-apoptotic stimuli can induce its proteasomal degradation allowing the translocation of AIFM1 to the nucleus to induce apoptosis (PubMed:22371500). Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081). Involved in actin stress fibers formation through its interaction with ARHGDIA and the regulation of the Rho signaling pathway (PubMed:17996375, PubMed:25961457). May thereby play a role in cell adhesion and migration, regulating for instance podocytes migration during development of the kidney (PubMed:25961457). Through the Rho signaling pathway may also regulate cell proliferation (By similarity)

The "KANK2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KANK2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets