KBTBD8: A Protein Involved in T Cell Activation and Cancer (G84541)

Target Name: KBTBD8

NCBI ID: G84541

KBTBD8

KBTBD8: A Protein Involved in T Cell Activation and Cancer

KBTBD8, also known as T-cell activation kelch repeat protein, is a protein that is expressed in T cells, a type of white blood cell that plays a crucial role in the immune system. T cells are responsible for recognizing and responding to foreign substances in the body, and they are a key part of the immune system's response to infections and viruses. KBTBD8 is a protein that is expressed in T cells and has been shown to play a role in the regulation of T cell activation and differentiation.

Disease and Treatment

One of the main goals of research into KBTBD8 is to understand how this protein contributes to the development and progression of various diseases. KBTBD8 has been shown to be involved in the regulation of T cell activation and differentiation, and it is thought to play a key role in the development of autoimmune diseases such as rheumatoid arthritis and multiple sclerosis.

In addition to its potential role in disease, KBTBD8 has also been shown to be a potential drug target. Researchers have identified several small molecules that can interact with KBTBD8 and have used these molecules to inhibit the activity of KBTBD8. These small molecules have the potential to be used to treat autoimmune diseases by reducing the activity of KBTBD8 and improving the function of T cells.

Another potential application of KBTBD8 is as a biomarker for tracking the progression of cancer. KBTBD8 has been shown to be expressed in various types of cancer cells and has been used as a biomarker for the diagnosis and prognosis of various types of cancer. Researchers are currently exploring the potential of using KBTBD8 as a marker for cancer diagnosis and treatment, with the goal of developing a new generation of cancer therapies that target this protein.

Conclusion

KBTBD8 is a protein that is expressed in T cells and has been shown to play a role in the regulation of T cell activation and differentiation. In addition to its potential role in disease, KBTBD8 has also been shown to be a potential drug target and a potential biomarker for cancer. Further research is needed to fully understand the role of KBTBD8 in the immune system and to develop new treatments for autoimmune diseases and cancer.

Protein Name: Kelch Repeat And BTB Domain Containing 8

Functions: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification (PubMed:26399832). The BCR(KBTBD8) complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832)

The "KBTBD8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KBTBD8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets