Target Name: KBTBD12
NCBI ID: G166348
Review Report on KBTBD12 Target / Biomarker Content of Review Report on KBTBD12 Target / Biomarker
KBTBD12
Other Name(s): Kelch domain containing 6 | kelch domain-containing protein 6 | Kelch repeat and BTB domain-containing protein 12 | KBTBC_HUMAN | FLJ46299 | kelch repeat and BTB (POZ) domain containing 12 | Kelch repeat and BTB domain containing 12, transcript variant 1 | kelch domain containing 6 | kelch repeat and BTB domain containing 12 | KLHDC6 | Kelch domain-containing protein 6 | KBTBD12 variant 1

KBTBD12: A Drug Target / Disease Biomarker

KBTBD12 is a protein that is expressed in the brain and is known for its role in the regulation of cell death. It has been shown to play a key role in the development of neurodegenerative diseases, such as Alzheimer's and Parkinson's.

Research has also suggested that KBTBD12 may have potential as a drug target. By blocking the activity of KBTBD12, researchers have found that they can reduce the damage caused by neurodegenerative diseases.

One way that KBTBD12 has been shown to contribute to neurodegenerative diseases is by regulating the production of glial cells, which are a type of immune cell that support the nervous system. Glial cells are thought to play a key role in the progression of neurodegenerative diseases, and researchers have suggested that KBTBD12 may be a target for drugs that could prevent or reverse the effects of these diseases.

Another potential mechanism by which KBTBD12 may contribute to neurodegenerative diseases is by contributing to the development of neurofibrillary tangles, which are thought to be a hallmark of neurodegenerative diseases. KBTBD12 has been shown to be involved in the production of these tangles, and researchers have suggested that it may be a target for drugs that could prevent or reverse the formation of these tangles.

In addition to its role in the regulation of cell death, KBTBD12 has also been shown to play a key role in the development and progression of neurodegenerative diseases. For example, studies have shown that KBTBD12 levels are reduced in the brains of individuals with Alzheimer's disease, and that these levels are associated with the severity of the disease.

Overall, the research suggests that KBTBD12 is a protein that is involved in the regulation of cell death and may be a potential drug target for the prevention or treatment of neurodegenerative diseases. Further research is needed to fully understand the role of KBTBD12 in these diseases and to develop effective treatments.

Protein Name: Kelch Repeat And BTB Domain Containing 12

The "KBTBD12 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KBTBD12 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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