KAT6B: Key Enzyme in Lysine Acetylation (G23522)

Target Name: KAT6B

NCBI ID: G23522

KAT6B

KAT6B: Key Enzyme in Lysine Acetylation

KAT6B, also known as Lysine acetyltransferase 6B, is a gene that encodes a protein located in the nucleus of the cell. The protein produced by this gene is known as KAT6B, and it is a key enzyme in the process of lysine acetylation.

In cellular signaling, lysine acetylation is a critical step in the regulation of various cellular processes, including cell division, apoptosis, and protein synthesis. The levels of lysine acetylation are regulated by a variety of factors, including the concentration of acetyl groups on specific lysine residues, the availability of factors that can either activate or inhibit lysine acetylation, and the overall level of protein synthesis in the cell.

KAT6B is a protein that is expressed in almost all cell types and is involved in the regulation of lysine acetylation. It is a 22-kDa protein that consists of 215 amino acid residues. The protein has a molecular weight of 23.9 kDa and a calculated pI of 6.9.

KAT6B is regulated by multiple factors, including DNA methylation, histone modification, and negative feedback loops. For example, studies have shown that KAT6B is regulated by the p53 protein, which is a well-known tumor suppressor gene that can induce cell apoptosis when it is activated. Additionally, KAT6B has been shown to be regulated by the lysine kinase (LK) pathway, which is a pathway that is involved in the regulation of protein synthesis and can be activated by various factors, including lysine and orphan Receptor tyrosine kinase (TK) 4.

KAT6B is also known as the KAT6B gene, and it is located on chromosome 11p36. It is a single gene that encodes a protein that is expressed in almost all cell types. The protein produced by this gene is known as KAT6B, and it is a 22-kDa protein that consists of 215 amino acid residues.

KAT6B is a protein that is involved in the regulation of lysine acetylation, which is a critical step in the regulation of various cellular processes. The levels of lysine acetylation are regulated by a variety of factors, including the concentration of acetyl groups on specific lysine residues , the availability of factors that can either activate or inhibit lysine acetylation, and the overall level of protein synthesis in the cell.

KAT6B is a protein that is expressed in almost all cell types and is involved in the regulation of lysine acetylation. It is a 22-kDa protein that consists of 215 amino acid residues, and it has a molecular weight of 23.9 kDa. The protein is regulated by multiple factors, including DNA methylation, histone modification, and negative feedback loops.

In conclusion, KAT6B is a protein that is involved in the regulation of lysine acetylation, which is a critical step in the regulation of various cellular processes. It is a 22-kDa protein that consists of 215 amino acid residues and is regulated by multiple factors , including DNA methylation, histone modification, and negative feedback loops. Further research is needed to fully understand the role of KAT6B in cellular signaling and to explore its potential as a drug target or biomarker.

Protein Name: Lysine Acetyltransferase 6B

Functions: Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity

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