Target Name: GFPT1
NCBI ID: G2673
Review Report on GFPT1 Target / Biomarker Content of Review Report on GFPT1 Target / Biomarker
GFPT1
Other Name(s): hexosephosphate aminotransferase 1 | GFPT1 variant 2 | Glutamine:fructose-6-phosphate amidotransferase 1 | GFPT1 variant 1 | glutamine:fructose-6-phosphate amidotransferase 1 | D-fructose-6-phosphate amidotransferase 1 | GFPT1_HUMAN | GFAT1 | CMSTA1 | Glutamine--fructose-6-phosphate transaminase 1, transcript variant 2 | GFPT | GFAT1m | Glucosamine-fructose-6-phosphate aminotransferase | glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | Glutamine--fructose-6-phosphate transaminase 1, transcript variant 1 | glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | GFAT | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | MSLG | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | Glutamine: fructose-6-phosphate amidotransferase-1 | glutamine--fructose-6-phosphate transaminase 1 | GFAT 1 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (isoform 1) | Hexosephosphate aminotransferase 1 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (isoform 2) | CMS12 | GFPT1L | GFA

GFPT1: A Potential Drug Target and Biomarker for Cellular Signaling

GFPT1 (hexosephosphate aminotransferase 1) is a gene that encodes a protein in theIMO gene family, which is responsible for the breakdown of glycophospholipids in cell membranes. It is a key enzyme in the pathway of hexosephosphate aminotransferase, which is involved in the breakdown of glycophospholipids and the transfer of phosphate groups to various amino acids.

GFPT1 is expressed in most tissues and cells of the body, including the brain, heart, liver, and kidneys. It is also highly expressed in the placenta, which supports the development and growth of new tissues. GFPT1 is a good candidate for drug targeting because of its unique localization in various tissues and its involvement in the process of cellular signaling.

GFPT1 functions as a critical enzyme in the pathway of hexosephosphate aminotransferase. This enzyme is responsible for the breakdown of glycophospholipids, which are the major components of cell membranes. The breakdown of these lipids allows the cell to receive essential nutrients and oxygen, while also allowing the cell to release waste products such as carbon dioxide and nitrogen.

GFPT1 is a key enzyme in the pathway of hexosephosphate aminotransferase, which is involved in the breakdown of glycophospholipids and the transfer of phosphate groups to various amino acids. The breakdown of glycophospholipids is critical for the growth and development of tissues and is a critical step in the process of cellular signaling.

GFPT1 is also involved in the regulation of cellular signaling. It is a key enzyme in the pathway of ubiquitin signaling, which is involved in the regulation of cellular signaling by the interaction between ubiquitin molecules and target proteins. GFPT1 plays a crucial role in the breakdown of glycophospholipids, which allows the cell to receive essential nutrients and oxygen and also allows the cell to release waste products such as carbon dioxide and nitrogen.

GFPT1 is also involved in the regulation of cellular signaling. It is a key enzyme in the pathway of signal transduction, which is involved in the regulation of cellular signaling by the interaction between ubiquitin molecules and target proteins. GFPT1 plays a crucial role in the breakdown of glycophospholipids, which allows the cell to receive essential nutrients and oxygen and also allows the cell to release waste products such as carbon dioxide and nitrogen.

GFPT1 is a potential drug target because of its unique localization in various tissues and its involvement in the process of cellular signaling. GFPT1 is also a good biomarker for tracking the effectiveness of drug treatments. By measuring the levels of GFPT1 in tissues and cells, researchers can determine the effectiveness of different treatments and monitor for any potential side effects.

In conclusion, GFPT1 (hexosephosphate aminotransferase 1) is a gene that encodes a protein involved in the breakdown of glycophospholipids and the transfer of phosphate groups to various amino acids. It is a key enzyme in the pathway of hexosephosphate aminotransferase and is involved in the regulation of cellular signaling. As a result, GFPT1 is a potential drug target and a good biomarker for tracking the effectiveness of drug treatments. Further research is needed to fully understand the role of GFPT1 in cellular signaling and its potential as a drug target.

Protein Name: Glutamine--fructose-6-phosphate Transaminase 1

Functions: Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes BMAL1 and CRY1 (By similarity). Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and its effects on hyaluronan synthesis that occur during tissue remodeling (PubMed:26887390)

The "GFPT1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GFPT1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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