Target Name: CHAMP1
NCBI ID: G283489
Review Report on CHAMP1 Target / Biomarker Content of Review Report on CHAMP1 Target / Biomarker
CHAMP1
Other Name(s): KIAA1802 | CHAP1_HUMAN | CHAMP1 variant 1 | CAMP | ZNF828 | CHAMP | C13orf8 | Chromosome alignment-maintaining phosphoprotein 1 | NEDHILD | Chromosome alignment maintaining phosphoprotein 1, transcript variant 1 | CHAMP1 variant 2 | MRD40 | zinc finger protein 828 | chromosome alignment maintaining phosphoprotein 1 | Chromosome alignment maintaining phosphoprotein 1, transcript variant 2 | Zinc finger protein 828

Discovering The Potential of CHAMP1 as A Drug Target Or Biomarker

CHAMP1 (KIAA1802) is a protein that is expressed in various tissues of the body, including the brain, heart, lungs, and liver. It is a key regulator of cell growth and differentiation, and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. In this article, we will discuss the research on CHAMP1 and its potential as a drug target or biomarker.

Background

CHAMP1 was first identified in the 1990s as a heat shock protein (HSP) that was expressed in response to increased thermal stress in cells. Since then, research has shown that CHAMP1 is involved in a wide range of cellular processes, including cell growth, differentiation, and stress response. CHAMP1 has also been shown to play a role in the regulation of inflammation and immune response.

In addition to its role in cellular processes, CHAMP1 is also a potential drug target or biomarker. Its involvement in a number of diseases has made it an attractive target for researchers to study, and its potential as a drug or biomarker has led to a significant amount of research in the field.

Diseases associated with CHAMP1

CHAMP1 has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

First, CHAMP1 has been shown to be involved in the development and progression of cancer. Several studies have shown that CHAMP1 is expressed in a variety of cancer types, including breast, ovarian, and prostate cancer. These studies have also shown that inhibiting CHAMP1 can lead to the inhibition of cancer cell growth and the inhibition of the angiogenic process, which is the process by which cancer cells form blood vessels and oxygenate their cells.

Second, CHAMP1 is also involved in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. These studies have shown that CHAMP1 is expressed in the brains of individuals with neurodegenerative diseases, and that inhibiting CHAMP1 can lead to the regression of neurodegenerative diseases.

Third, CHAMP1 is also involved in the development and progression of autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis. These studies have shown that CHAMP1 is expressed in the tissues of individuals with autoimmune disorders, and that inhibiting CHAMP1 can lead to the regression of autoimmune disorders.

Potential as a drug target

CHAMP1's involvement in the development and progression of these diseases makes it an attractive target for drug development. Several studies have shown that inhibiting CHAMP1 can lead to the inhibition of the angiogenic process, which is the process by which cancer cells form blood vessels and oxygenate their cells, and the regression of neurodegenerative diseases and autoimmune disorders.

In addition, CHAMP1 has also been shown to play a role in the regulation of inflammation and immune response, which makes it an attractive target for drugs that are designed to modulate these processes.

Potential as a biomarker

CHAMP1 has also been shown to be a potential biomarker for a number of diseases. Its involvement in the regulation of cell growth and differentiation makes it an attractive target for biomarkers that are designed to monitor the effects of drugs on cellular processes.

In addition, CHAMP1's involvement in the regulation of inflammation and immune response makes it an attractive target for biomarkers that are designed to monitor the effects of drugs on inflammation and immune response.

Conclusion

In conclusion, CHAMP1 is a protein that is involved in a wide range of cellular processes, including

Protein Name: Chromosome Alignment Maintaining Phosphoprotein 1

Functions: Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore

The "CHAMP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CHAMP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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