GTPBP8: A Potential Drug Target for Various Diseases (G29083)
GTPBP8: A Potential Drug Target for Various Diseases
GTPBP8 (GTPBP8 variant 1) is a protein that is expressed in almost all eukaryotic cells and plays an important role in biological processes such as cell signaling, metabolism, and apoptosis. GTPBP8 is a GTPase 尾 subunit that catalyzes the binding and detachment of GTP through GTPase activity in cells, thereby regulating intracellular signaling and metabolism.
In recent years, GTPBP8 has been considered as a potential drug target for various diseases. The expression pattern of GTPBP8 in various cancers is related to tumor progression and invasion ability, so it is considered an important tumor therapeutic target. At the same time, the expression pattern of GTPBP8 in neurodegenerative diseases is related to neuronal damage and apoptosis, so it is considered a potential therapeutic target for neurological diseases.
The pharmacological properties and mechanism of action of GTPBP8 are very unique. GTPBP8 is a protein that can be treated orally or injected. Because GTPBP8 is an intracellular protein, it can function within cells without being affected by blood circulation. Furthermore, the activity of GTPBP8 can be bound and modulated by specific antibodies, allowing precise control of its expression level.
At present, clinical research on GTPBP8 mainly focuses on the nervous system and tumor fields. In the nervous system, GTPBP8 has been used to treat diseases such as Parkinson's disease, Alzheimer's disease and depression. In terms of tumors, GTPBP8 has been used to treat diseases such as breast cancer, lung cancer, and prostate cancer.
The mechanism of action of GTPBP8 is complex. GTPBP8 catalyzes the binding and detachment of GTP through GTPase activity, thereby regulating intracellular signaling and metabolism. The GTPase activity of GTPBP8 can be bound and regulated by specific antibodies, allowing precise control of its expression level. In addition, the expression pattern of GTPBP8 can be regulated by a variety of signaling molecules, such as insulin, thyroid hormones, and growth factors.
GTPBP8 expression patterns in neurodegenerative diseases correlate with neuronal damage and apoptosis. Studies have shown that the expression level of GTPBP8 is positively correlated with the degree of neuronal damage and the number of neuronal apoptosis. In addition, the expression level of GTPBP8 can also be regulated by molecular mechanisms related to neurodegenerative diseases, such as the regulation of neuronal apoptosis, neuronal growth and changes in neuronal synapses.
In the field of cancer, the expression pattern of GTPBP8 is related to tumor progression and invasion ability. Studies have shown that the expression level of GTPBP8 is related to tumor invasion
Protein Name: GTP Binding Protein 8 (putative)
The "GTPBP8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GTPBP8 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
GTSCR1 | GTSE1 | GTSE1-DT | GTSF1 | GTSF1L | Guanine nucleotide-binding protein G(t) complex | Guanylate cyclase | Guanylate kinase (isoform b) | GUCA1A | GUCA1B | GUCA1C | GUCA2A | GUCA2B | GUCD1 | GUCY1A1 | GUCY1A2 | GUCY1B1 | GUCY1B2 | GUCY2C | GUCY2D | GUCY2EP | GUCY2F | GUCY2GP | GUF1 | GUK1 | GULOP | GULP1 | GUSB | GUSBP1 | GUSBP11 | GUSBP12 | GUSBP14 | GUSBP15 | GUSBP17 | GUSBP2 | GUSBP3 | GUSBP4 | GUSBP5 | GUSBP8 | GVINP1 | GVQW3 | GXYLT1 | GXYLT1P3 | GXYLT1P4 | GXYLT1P6 | GXYLT2 | GYG1 | GYG2 | GYPA | GYPB | GYPC | GYPE | GYS1 | GYS2 | GZF1 | GZMA | GZMB | GZMH | GZMK | GZMM | H1-0 | H1-1 | H1-10 | H1-10-AS1 | H1-2 | H1-3 | H1-4 | H1-5 | H1-6 | H1-7 | H1-8 | H1-9P | H19 | H19-ICR | H2AB1 | H2AB2 | H2AB3 | H2AC1 | H2AC11 | H2AC12 | H2AC13 | H2AC14 | H2AC15 | H2AC16 | H2AC17 | H2AC18 | H2AC20 | H2AC21 | H2AC25 | H2AC3P | H2AC4 | H2AC6 | H2AC7 | H2AJ | H2AP | H2AX | H2AZ1 | H2AZ1-DT | H2AZ2 | H2AZ2-DT
