Zinc Finger Protein 12D: Potential Drug Target and Biomarker (G340152)

Target Name: ZC3H12D

NCBI ID: G340152

ZC3H12D

Zinc Finger Protein 12D: Potential Drug Target and Biomarker

Zinc finger CCCH domain-containing protein 12D (ZC3H12D) is a protein that is expressed in various tissues of the body, including the brain, heart, and gastrointestinal tract. It is characterized by the presence of a zinc finger domain, which is a common structural feature that is found in many proteins that play important roles in various cellular processes. ZC3H12D is a member of the Zinc finger gene family, which is known for the presence of a zinc finger domain in their sequence.

The ZC3H12D protein is involved in a variety of cellular processes that are important for normal development and function. One of the main functions of ZC3H12D is to regulate the expression of other genes. This is done through the interaction of ZC3H12D with the appropriate transcription factors, which allows it to either activate or inhibit the activity of these factors.

In addition to its role in gene regulation, ZC3H12D is also involved in the regulation of cellular signaling pathways. This is done through the interaction of ZC3H12D with various signaling molecules, including tyrosines, which are involved in the signaling of many cellular processes.

One of the unique features of ZC3H12D is its structure. It consists of a single polypeptide chain that is composed of 121 amino acid residues. The protein has a characteristic hour-shaped appearance due to the presence of a variable region that includes several short amino acid residues on the N-terminus and a C-terminus that is involved in its interactions with other proteins.

The ZC3H12D gene is located on chromosome 6p21.3 and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is because of its involvement in various cellular processes that are important for normal development and function.

One of the potential applications of ZC3H12D as a drug target or biomarker is its involvement in the regulation of cellular signaling pathways. Many diseases are caused by the disruption of normal cellular signaling pathways, and ZC3H12D may be a useful target for the development of new therapies. For example, ZC3H12D has been shown to be involved in the regulation of the activity of the tyrosine kinase PDGFR-尾, which is involved in the development of many types of cancer. Therefore, inhibitors of ZC3H12D may be a useful approach for the treatment of cancer.

In addition to its potential as a drug target, ZC3H12D may also be a useful biomarker for the diagnosis and monitoring of various diseases. For example, its expression has been shown to be involved in the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Therefore, ZC3H12D may be a useful biomarker for the diagnosis and monitoring of these conditions.

Overall, ZC3H12D is a protein that is involved in a variety of cellular processes that are important for normal development and function. Its structure and function make it a potential target for the development of new therapies, as well as a useful biomarker for the diagnosis and monitoring of various diseases. Further research is needed to fully understand the role of ZC3H12D in these processes and its potential as a drug target or biomarker.

Protein Name: Zinc Finger CCCH-type Containing 12D

Functions: May regulate cell growth likely by suppressing RB1 phosphorylation (PubMed:19531561). May function as RNase and regulate the levels of target RNA species (Potential). In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages (PubMed:26134560). Serve as a tumor suppressor in certain leukemia cells (PubMed:17210687). Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation (PubMed:19531561)

The "ZC3H12D Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZC3H12D comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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