ZCCHC4: A Potential Drug Target and Biomarker for Zinc Finger Proteins

Target Name: ZCCHC4

NCBI ID: G29063

ZCCHC4

ZCCHC4: A Potential Drug Target and Biomarker for Zinc Finger Proteins

Introduction

Zinc finger proteins (ZFPs) are a family of non-coding RNAs that play a crucial role in various cellular processes. One of the subfamilies of ZFPs, the DHHC domain-containing zinc finger proteins (ZCCHC4), have been identified as potential drug targets and biomarkers. In this article, we will explore the ZCCHC4 protein, its functions, potential drug targets, and its potential as a biomarker for various diseases.

Structure and Function

The ZCCHC4 protein is a 21-kDa protein that is expressed in various tissues and cells. It is composed of a unique domain that consists of a conserved zinc finger core, a short amino acid residues, and a C-terminal transmembrane region ( TMD). The ZCCHC4 protein functions as a regulator of various cellular processes, including cell growth, differentiation, and inflammation.

One of the unique features of the ZCCHC4 protein is its ability to form a binary complex with other proteins through its Zn2+-dependent interaction. This interaction allows the ZCCHC4 protein to regulate the activity of multiple target proteins by modulating their phosphorylation status. Additionally, the ZCCHC4 protein can also form a ternary complex with the protein p16INK4a and the zinc ion. This ternary interaction plays a crucial role in the regulation of cell growth, apoptosis, and inflammation.

Potential Drug Targets

The ZCCHC4 protein has been identified as a potential drug target due to its involvement in various cellular processes that are associated with various diseases. One of the potential drug targets for ZCCHC4 is the regulation of cell apoptosis. The ZCCHC4 protein has been shown to play a negative role in the regulation of cell apoptosis, which is associated with the development of various diseases, including cancer. Additionally, the ZCCHC4 protein has also been shown to be involved in the regulation of cell growth, which is associated with the development of various diseases, including cardiovascular diseases.

In addition to its involvement in cell apoptosis and growth, the ZCCHC4 protein has also been shown to play a role in the regulation of inflammation. The ZCCHC4 protein has been shown to be involved in the regulation of inflammation, which is associated with the development of various diseases, including autoimmune diseases.

Potential Biomarkers

The ZCCHC4 protein has the potential to serve as a biomarker for various diseases due to its involvement in various cellular processes that are associated with the development of these diseases. One of the potential biomarkers for the ZCCHC4 protein is its ability to form a binary complex with other proteins, which can be used to monitor the activity of the ZCCHC4 protein. Additionally, the ZCCHC4 protein has been shown to be involved in the regulation of cell apoptosis, which can be used as a biomarker for the diagnosis and treatment of Apoptosis-related diseases.

Conclusion

In conclusion, the ZCCHC4 protein is a unique protein that functions as a regulator of various cellular processes and has the potential to serve as a drug target and biomarker for various diseases. Its unique ability to form a binary and ternary complex with other proteins makes it an attractive target for drug development. Additionally, its involvement in the regulation of cell apoptosis and growth, as well as its involvement in the regulation of inflammation, make it a promising biomarker for the diagnosis and treatment of various diseases.

Protein Name: Zinc Finger CCHC-type Containing 4

Functions: rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA (PubMed:30531910, PubMed:31328227, PubMed:31799605, PubMed:31695039). N6-methylation of adenine(4220) in 28S rRNA is required for translation (PubMed:30531910, PubMed:31799605)

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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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