Zinc Finger Protein ZC3H18: A Potential Drug Target Or Biomarker

Target Name: ZC3H18

NCBI ID: G124245

ZC3H18

Zinc Finger Protein ZC3H18: A Potential Drug Target Or Biomarker

Zinc finger CCCH-type containing 18 (ZC3H18) is a protein that has been identified as a potential drug target or biomarker in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Zinc finger proteins are a family of transducing RNA-binding proteins , they play important biological roles in organisms.

ZC3H18 is an 18 kDa protein with unique structural domains including a zinc finger, a short tail, and a capital J (JUCA) domain. Zinc fingers are specialized protein domains, usually composed of a single polypeptide chain, that have the ability to bind transducing RNA with high specificity. The short tail and capital letter J domain are responsible for protein stability and intracellular localization.

In recent years, researchers have conducted in-depth studies on the functions of ZC3H18. The results show that ZC3H18 plays an important role in a variety of biological processes, including cell proliferation, differentiation, and tumor formation.

In cancer, ZC3H18 was found to be upregulated in multiple types of tumors. For example, in breast cancer, the expression level of ZC3H18 is significantly elevated, while in prostate and colon cancer, it is lower. In addition, the expression level of ZC3H18 is also related to tumor invasion and metastasis. Therefore, ZC3H18 may be a potential tumor target.

ZC3H18 also plays an important role in neurodegenerative diseases. For example, in rats, overexpression of ZC3H18 is associated with neuronal death and synaptic damage. In Alzheimer's disease, ZC3H18 expression levels are associated with neuronal loss and cognitive decline. These studies suggest that ZC3H18 may be an important target for neurodegenerative diseases.

ZC3H18 also plays an important role in immune diseases. For example, expression levels of ZC3H18 are often elevated in autoimmune diseases. In addition, ZC3H18 is also related to immune cell functions, such as T cell activation and proliferation. Therefore, ZC3H18 may be a potential immune disease target.

In addition to its role in disease, ZC3H18 may also serve as a drug target in drug research. For example, studies have shown that ZC3H18 can be used as a target for anti-tumor drugs, including antimetabolites, immunosuppressants, and apoptosis inducers. In addition, ZC3H18 can also be used as a biomarker for neurodegenerative diseases and immune diseases, providing important reference value for disease diagnosis and treatment.

In summary, ZC3H18 is a protein with important biological effects and plays an important role in a variety of diseases. With the continuous advancement of technology, researchers' interest and efforts will help to further study the biological functions and pharmacological significance of ZC3H18, providing new ideas and methods for the treatment and diagnosis of various diseases.

Protein Name: Zinc Finger CCCH-type Containing 18

The "ZC3H18 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZC3H18 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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