TMEM225: A Potential Drug Target and Biomarker (G338661)

Target Name: TMEM225

NCBI ID: G338661

TMEM225

TMEM225: A Potential Drug Target and Biomarker

TMEM225 (SPATA47) is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, and gastrointestinal tract. It is a member of the SPATA gene family, which is known for the development of functional tissues after gene knockdown. TMEM225 has been shown to play a role in a variety of biological processes, including cell signaling, DNA replication, and stress response.

One of the most promising aspects of TMEM225 is its potential as a drug target. TMEM225 has been shown to interact with a variety of small molecules, including drugs that are used to treat a range of diseases. For example, TMEM225 has been shown to interact with inhibitors of the protein kinase A (PKA), which is a known regulator of many cellular processes. These interactions suggest that TMEM225 may be a useful target for drugs that are used to treat PKA-related disorders.

In addition to its potential as a drug target, TMEM225 has also been shown to be a potential biomarker for a variety of diseases. For example, TMEM225 has been shown to be expressed in the brains of individuals with Alzheimer's disease, which is a leading cause of dementia. These findings suggest that TMEM225 may be a useful biomarker for the diagnosis and treatment of Alzheimer's disease.

Another promising aspect of TMEM225 is its role in the regulation of cell signaling. TMEM225 has been shown to play a role in the regulation of several signaling pathways, including the cell signaling pathway associated with the protein serine/threonine kinase (S/TK). This pathway is involved in the regulation of a wide range of cellular processes, including cell growth, differentiation, and stress response.

TMEM225 may also be a useful target for drugs that are used to treat a variety of neuropsychiatric disorders. For example, TMEM225 has been shown to play a role in the regulation of the neurotransmitter serotonin, which is involved in a wide range of physiological processes, including mood regulation and appetite. These findings suggest that TMEM225 may be a useful target for drugs that are used to treat neuropsychiatric disorders.

In conclusion, TMEM225 is a protein that has been shown to play a role in a variety of biological processes, including cell signaling and stress response. Its potential as a drug target and as a biomarker make it an attractive target for further research. Further studies are needed to fully understand the role of TMEM225 in these processes and to determine its potential as a drug or biomarker.

Protein Name: Transmembrane Protein 225

Functions: Probably inhibits protein phosphatase 1 (PP1) in sperm via binding to catalytic subunit PPP1CC

The "TMEM225 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMEM225 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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