TMEM63B: A Transmembrane Protein for Drug Targets and Biomarkers

Target Name: TMEM63B

NCBI ID: G55362

TMEM63B

TMEM63B: A Transmembrane Protein for Drug Targets and Biomarkers

TMEM63B (Transmembrane Protein 63B) is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and intestine. Its primary function is to regulate the movement of ions and molecules across the cell membrane. It plays a crucial role in maintaining the proper functioning of various physiological processes in the body, including the regulation of ion and water balance, as well as the maintenance of cell signaling pathways.

Recent studies have suggested that TMEM63B may have potential as a drug target or biomarker. In this article, we will explore the biology and potential clinical applications of TMEM63B.

Biography of TMEM63B

TMEM63B is a member of the superfamily of transmembrane proteins, which are involved in the regulation of ion and water transport across cell membranes. These proteins are characterized by the presence of an extracellular domain, a transmembrane segment, and an intracellular segment. TMEM63B is characterized by a unique feature, an N-terminal transmembrane domain, which is responsible for its unique structure and function.

TMEM63B is expressed in a variety of tissues, including the brain, heart, kidneys, and intestine. It is highly expressed in the brain, where it is found in the postsynaptic density of neurons and glial cells. TMEM63B is also expressed in other tissues, including the heart, kidneys, and intestine, where it plays a role in the regulation of ion and water transport.

Potential Applications of TMEM63B

TMEM63B has been suggested as a potential drug target due to its unique structure and function. The N-terminal transmembrane domain of TMEM63B is responsible for its unique structure and function. This domain is involved in the regulation of the movement of ions and molecules across the cell membrane, which is crucial for the proper functioning of various physiological processes in the body.

In addition to its potential as a drug target, TMEM63B has also been suggested as a potential biomarker for various diseases. The regulation of ion and water transport by TMEM63B is involved in the regulation of various physiological processes in the body, including the regulation of blood pressure, blood glucose levels, and the regulation of the balance of salts and water in the body.

TMEM63B has also been shown to play a role in the development and progression of certain diseases, such as cancer. Studies have shown that TMEM63B is highly expressed in various tissues of cancer, and that its regulation is disrupted in these diseases. This suggests that TMEM63B may be a useful biomarker for the diagnosis and treatment of cancer.

Conclusion

In conclusion, TMEM63B is a unique and highly expressed protein that plays a critical role in the regulation of ion and water transport across cell membranes. Its N-terminal transmembrane domain, which is responsible for its unique structure and function, makes it a potential drug target. In addition to its potential as a drug target, TMEM63B has also been suggested as a potential biomarker for various diseases, including cancer. Further research is needed to fully understand the biology and potential clinical applications of TMEM63B.

Protein Name: Transmembrane Protein 63B

Functions: Acts as an osmosensitive calcium-permeable cation channel (By similarity). Mechanosensitive ion channel that converts mechanical stimuli into a flow of ion (By similarity)

The "TMEM63B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMEM63B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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