Target Name: TMEM45B
NCBI ID: G120224
Review Report on TMEM45B Target / Biomarker Content of Review Report on TMEM45B Target / Biomarker
TMEM45B
Other Name(s): Transmembrane protein 45B | transmembrane protein 45B | TM45B_HUMAN | FLJ40787 | Transmembrane protein 45B, transcript variant 2 | TMEM45B variant 2

TMEM45B: A Drug Target / Disease Biomarker

TMEM45B, also known as transmembrane protein TMEM45B or protein TMEM45B, is a protein that is expressed in many different tissues throughout the body. It is a member of the transmembrane protein family, which means that it is involved in the transportation of molecules across the cell membrane. TMEM45B is also known for its role in the development and progression of various diseases, including cancer. As a result, TMEM45B has generated a lot of interest as a potential drug target or biomarker.

TMEM45B is a protein that is expressed in many different tissues throughout the body, including the brain, heart, liver, and pancreas. It is a member of the transmembrane protein family, which means that it is involved in the transportation of molecules across the cell membrane. TMEM45B is a 22kDa protein that consists of 151 amino acid residues. It has a unique structure that is composed of a transmembrane region and an extracellular region. The transmembrane region is responsible for the protein's ability to interact with other molecules on the cell surface, while the extracellular region is responsible for the protein's ability to interact with other components of the cell.

One of the most significant functions of TMEM45B is its role in the development and progression of various diseases, including cancer. TMEM45B has been shown to be involved in the regulation of cell growth, cell survival, and cell migration. It has also been shown to play a role in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. In addition, TMEM45B has been shown to be involved in the regulation of inflammation, which is a major risk factor for many diseases.

As a result of its involvement in the development and progression of various diseases, TMEM45B has generated a lot of interest as a potential drug target or biomarker. Researchers are studying TMEM45B to see if it can be used to treat a variety of diseases. For example, some researchers are studying TMEM45B to see if it can be used to treat cancer by inhibiting its ability to promote cell growth and survival. Other researchers are studying TMEM45B to see if it can be used to treat neurodegenerative diseases by increasing the levels of the protein in the brain.

In addition to its potential as a drug target or biomarker, TMEM45B is also of interest to researchers because of its unique structure and the way it functions. TMEM45B is a 22kDa protein that consists of 151 amino acid residues. It has a unique structure that is composed of a transmembrane region and an extracellular region. The transmembrane region is responsible for the protein's ability to interact with other molecules on the cell surface, while the extracellular region is responsible for the protein's ability to interact with other components of the cell. TMEM45B's unique structure makes it an ideal candidate for study as a potential drug target or biomarker.

Overall, TMEM45B is a protein that has generated a lot of interest as a potential drug target or biomarker due to its involvement in the development and progression of various diseases and its unique structure. While further research is needed to fully understand the role of TMEM45B in these processes, it is clear that it has the potential to be a valuable tool in the fight against disease.

Protein Name: Transmembrane Protein 45B

Functions: Plays a role in innate immunity (PubMed:35938871). Mechanistically, promotes alphaviruses RNA degradation by interacting with the viral polymerase nsP4 and the mRNA-capping enzyme nsP1 and thereby interfering with the interaction between viral RNA and nsP1.(PubMed:35938871)

The "TMEM45B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMEM45B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TMEM47 | TMEM50A | TMEM50B | TMEM51 | TMEM51-AS1 | TMEM51-AS2 | TMEM52 | TMEM52B | TMEM53 | TMEM54 | TMEM59 | TMEM59L | TMEM60 | TMEM61 | TMEM62 | TMEM63A | TMEM63B | TMEM63C | TMEM64 | TMEM65 | TMEM67 | TMEM68 | TMEM69 | TMEM70 | TMEM71 | TMEM72 | TMEM72-AS1 | TMEM74 | TMEM74B | TMEM78 | TMEM79 | TMEM80 | TMEM81 | TMEM82 | TMEM86A | TMEM86B | TMEM87A | TMEM87B | TMEM88 | TMEM88B | TMEM89 | TMEM8B | TMEM9 | TMEM91 | TMEM92 | TMEM94 | TMEM95 | TMEM97 | TMEM98 | TMEM9B | TMEM9B-AS1 | TMF1 | TMIE | TMIGD1 | TMIGD2 | TMIGD3 | TMLHE | TMLHE-AS1 | TMOD1 | TMOD2 | TMOD3 | TMOD4 | TMPO | TMPO-AS1 | TMPPE | TMPRSS11A | TMPRSS11B | TMPRSS11BNL | TMPRSS11D | TMPRSS11E | TMPRSS11F | TMPRSS12 | TMPRSS13 | TMPRSS15 | TMPRSS2 | TMPRSS3 | TMPRSS4 | TMPRSS5 | TMPRSS6 | TMPRSS7 | TMPRSS9 | TMSB10 | TMSB15A | TMSB15B | TMSB4X | TMSB4XP1 | TMSB4XP2 | TMSB4XP4 | TMSB4XP8 | TMSB4Y | TMTC1 | TMTC2 | TMTC3 | TMTC4 | TMUB1 | TMUB2 | TMX1 | TMX2 | TMX2-CTNND1 | TMX3