Target Name: TMEM253
NCBI ID: G643382
Review Report on TMEM253 Target / Biomarker Content of Review Report on TMEM253 Target / Biomarker
TMEM253
Other Name(s): TM253_HUMAN | Transmembrane protein 253 | Transmembrane protein 253 (isoform 1) | C14orf95 | NCRNA00220 | C14orf176 | transmembrane protein C14orf176 | Transmembrane protein 253, transcript variant 2 | transmembrane protein 253 | Transmembrane protein C14orf176 | TMEM253 variant 2

TMEM253: A Potential Drug Target Or Biomarker

TMEM253 (TM253_HUMAN), also known as humanTMEM253, is a protein that is expressed in various tissues of the human body. It is a member of the transmembrane protein family, which means that it spans the cell membrane and functions as a protein that interacts with other proteins and molecules within the same or different cell types. TMEM253 has been shown to play a role in a variety of biological processes, including cell signaling, cell adhesion, and tissue repair. As a result, TMEM253 has potential as a drug target or biomarker.

TMEM253 is a 21-kDa protein that is expressed in various tissues of the human body, including brain, heart, liver, and muscle. It is characterized by a transmembrane domain and a cytoplasmic tail. The transmembrane domain is responsible for the protein's ability to interact with other proteins and molecules on the cell membrane. This interaction is crucial for the protein's function, as it allows TMEM253 to regulate various cellular processes that are critical for overall health and disease.

One of the key functions of TMEM253 is its role in cell signaling. TMEM253 has been shown to play a role in the regulation of cell proliferation, differentiation, and survival. It has been shown to interact with various signaling molecules, including TGF-β, NF-kappa-B, and ERK. These interactions allow TMEM253 to regulate the expression of genes that are involved in cell signaling and growth.

TMEM253's role in cell adhesion is another area of its potential as a drug target or biomarker. Adhesion is the process by which cells stick together to form tissues and organs. TMEM253 has been shown to play a role in the regulation of cell adhesion, as it has been shown to interact with various adhesion molecules, including cadherins and immunoglobulin-like cell adhesion molecules (Ig-CAMs). These interactions allow TMEM253 to regulate the stickiness of cells to each other and to their surrounding tissues, which is important for the formation and maintenance of tissues and organs.

In addition to its role in cell signaling and adhesion, TMEM253 has also been shown to play a role in tissue repair. TMEM253 has been shown to interact with various repair proteins, including DNA repair proteins and cell survival proteins. These interactions allow TMEM253 to regulate the repair of damaged tissues and to promote the growth and proliferation of cells that are involved in tissue repair.

TMEM253's potential as a drug target or biomarker is due to its unique structure and its involvement in various biological processes. As more research is conducted on TMEM253, it is likely that additional functions will be discovered that will further its potential as a drug target or biomarker.

In conclusion, TMEM253 is a protein that has been shown to play a role in various biological processes, including cell signaling, cell adhesion, and tissue repair. As a result, TMEM253 has potential as a drug target or biomarker, and further research is needed to fully understand its functions and to develop safe and effective drugs that target TMEM253.

Protein Name: Transmembrane Protein 253

The "TMEM253 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMEM253 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TMEM254 | TMEM254-AS1 | TMEM255A | TMEM255B | TMEM256 | TMEM256-PLSCR3 | TMEM257 | TMEM258 | TMEM259 | TMEM26 | TMEM260 | TMEM263 | TMEM265 | TMEM266 | TMEM267 | TMEM268 | TMEM270 | TMEM271 | TMEM272 | TMEM273 | TMEM30A | TMEM30A-DT | TMEM30B | TMEM30CP | TMEM31 | TMEM33 | TMEM35A | TMEM37 | TMEM38A | TMEM38B | TMEM39A | TMEM39B | TMEM40 | TMEM41A | TMEM41B | TMEM42 | TMEM43 | TMEM44 | TMEM44-AS1 | TMEM45A | TMEM45B | TMEM47 | TMEM50A | TMEM50B | TMEM51 | TMEM51-AS1 | TMEM51-AS2 | TMEM52 | TMEM52B | TMEM53 | TMEM54 | TMEM59 | TMEM59L | TMEM60 | TMEM61 | TMEM62 | TMEM63A | TMEM63B | TMEM63C | TMEM64 | TMEM65 | TMEM67 | TMEM68 | TMEM69 | TMEM70 | TMEM71 | TMEM72 | TMEM72-AS1 | TMEM74 | TMEM74B | TMEM78 | TMEM79 | TMEM80 | TMEM81 | TMEM82 | TMEM86A | TMEM86B | TMEM87A | TMEM87B | TMEM88 | TMEM88B | TMEM89 | TMEM8B | TMEM9 | TMEM91 | TMEM92 | TMEM94 | TMEM95 | TMEM97 | TMEM98 | TMEM9B | TMEM9B-AS1 | TMF1 | TMIE | TMIGD1 | TMIGD2 | TMIGD3 | TMLHE | TMLHE-AS1 | TMOD1