Target Name: SPRR2D
NCBI ID: G6703
Review Report on SPRR2D Target / Biomarker Content of Review Report on SPRR2D Target / Biomarker
SPRR2D
Other Name(s): small proline rich protein 2D | Small proline-rich protein 2D | SPR-2D | SPRR2D variant 1 | Small proline rich protein 2D, transcript variant 1 | small proline-rich protein II | SPR-II | SPR2D_HUMAN | Small proline-rich protein II

SPRR2D: A Potential Drug Target and Biomarker for Proline-Rich Protein 2D

Proline-rich proteins (PRPs) are a class of unique biomarkers that have been identified in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. These proteins are composed of four amino acids: alanine, glutamic acid, proline, and aspartic acid, which are arranged in a specific order to give them their unique structure. PRPs have been shown to play a critical role in the development and progression of these diseases, and as a result, they have become a focus of intense research in the pharmaceutical industry.

One of the most promising avenues for targeting PRPs is the SPRR2D protein. SPRR2D is a PRP that is expressed in various tissues, including the brain, heart, and liver. It is composed of four amino acids, which are similar to those in PRPs, but with a unique side chain. SPRR2D has been shown to be involved in various physiological processes in the body, including cell signaling, inflammation, and stress response.

SPRR2D has also been shown to be a potential drug target. Studies have shown that SPRR2D can interact with various drug molecules, including small molecules, peptides, and antibodies. Additionally, SPRR2D has been shown to be involved in the regulation of cellular processes that are important for drug response, including cell adhesion, migration, and angiogenesis. These properties make SPRR2D an attractive target for drug development.

In addition to its potential as a drug target, SPRR2D has also been shown to be a potential biomarker for various diseases. Its unique structure and expression pattern make it an ideal candidate for diagnostic tests. For example, SPRR2D has been shown to be expressed in the brains of individuals with Alzheimer's disease, and its levels have been associated with the severity of cognitive impairment in these individuals. Additionally, SPRR2D has been shown to be expressed in the blood vessels of individuals with cardiovascular disease, and its levels have been associated with the risk of cardiovascular events in these individuals.

In conclusion, SPRR2D is a PRP that has shown promise as a potential drug target and biomarker for various diseases. Its unique structure and expression pattern make it an ideal candidate for further research in these areas. Further studies are needed to fully understand the role of SPRR2D in the development and progression of various diseases, including its potential as a drug target and biomarker.

Protein Name: Small Proline Rich Protein 2D

Functions: Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane

The "SPRR2D Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPRR2D comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SPRR2E | SPRR2F | SPRR2G | SPRR3 | SPRR4 | SPRTN | SPRY1 | SPRY2 | SPRY3 | SPRY4 | SPRY4-AS1 | SPRY4-IT1 | SPRYD3 | SPRYD4 | SPRYD7 | SPSB1 | SPSB2 | SPSB3 | SPSB4 | SPTA1 | SPTAN1 | SPTB | SPTBN1 | SPTBN2 | SPTBN4 | SPTBN5 | SPTLC1 | SPTLC1P1 | SPTLC2 | SPTLC3 | SPTSSA | SPTSSB | SPTY2D1 | SPX | SPZ1 | SQLE | SQOR | SQSTM1 | SRA1 | SRARP | SRBD1 | SRC | SRCAP | SRCIN1 | SRD5A1 | SRD5A1P1 | SRD5A2 | SRD5A3 | SRD5A3-AS1 | SREBF1 | SREBF2 | SREBF2-AS1 | SREK1 | SREK1IP1 | SRF | SRFBP1 | SRGAP1 | SRGAP2 | SRGAP2B | SRGAP2C | SRGAP2D | SRGAP3 | SRGN | SRI | SRI-AS1 | SRL | SRM | SRMS | SRP14 | SRP14-DT | SRP19 | SRP54 | SRP54-AS1 | SRP68 | SRP72 | SRP9 | SRP9P1 | SRPK1 | SRPK2 | SRPK3 | SRPRA | SRPRB | SRPX | SRPX2 | SRR | SRRD | SRRM1 | SRRM1P1 | SRRM2 | SRRM2-AS1 | SRRM3 | SRRM4 | SRRM5 | SRRT | SRSF1 | SRSF10 | SRSF11 | SRSF12 | SRSF2 | SRSF3