OR8G3P: The Olfactory Receptor, Family 8, Subfamily G, Member 3 Pseudogene as a Drug Target and Biomarker

Target Name: OR8G3P

NCBI ID: G387815

OR8G3P

Other Name(s): Olfactory receptor, family 8, subfamily G, member 3 pseudogene | olfactory receptor OR11-297 | olfactory receptor family 8 subfamily G member 3 pseudogene

OR8G3P: The Olfactory Receptor, Family 8, Subfamily G, Member 3 Pseudogene as a Drug Target and Biomarker

Smell is a crucial sense, and the olfactory receptor, family 8, subfamily G, member 3 (OR8G3P) plays a significant role in human perception and behavior. OR8G3P is a pseudogene, which means it is a non-functional gene that has lost its protein product due to a mutation. Despite its non-functional state, OR8G3P has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and psychiatric disorders.

OR8G3P is a member of the olfactory receptor family, which is a large gene family that includes over 400 genes that encode proteins involved in smell and taste perception. The OR8G3P gene is located on chromosome 6p22 and has been annotated with several potential transmembrane and cytoplasmic proteins. OR8G3P is a single gene that encodes a protein with a predicted molecular weight of 11.4 kDa.

OR8G3P functions as a olfactory receptor, which is responsible for transmitting sensory information from the nose and sinuses to the brain. The olfactory receptor is a transmembrane protein that is expressed in the sensory neurons, including those in the olfactory system. OR8G3P is involved in the development and maintenance of the sensory system, and its expression has been implicated in various neurological and psychiatric disorders.

OR8G3P has been shown to be involved in several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. These disorders are characterized by the progressive loss of brain cells and the accumulation of neurofibrillary tangles and other abnormally formed proteins. The exact mechanisms by which OR8G3P contributes to these disorders are not yet fully understood, but it is thought to play a role in the regulation of neurotransmitter release and cell signaling.

In addition to its involvement in neurodegenerative diseases, OR8G3P has also been shown to be involved in cancer. Studies have suggested that OR8G3P may be a potential therapeutic target for cancer, particularly in the context of airway cancer. In airway cancer, which is a common form of cancer that arises from the cells that line the airways of the lungs, OR8G3P has been shown to be expressed in the cancer cells and may contribute to their growth and survival.

Furthermore, OR8G3P has also been shown to be involved in psychiatric disorders, including depression and anxiety. Studies have suggested that OR8G3P may be involved in the regulation of neurotransmitter release and cell signaling in the brain, and that its dysfunction in these disorders may contribute to the symptoms of depression and anxiety.

Despite its potential as a drug target and biomarker, OR8G3P is not yet a widely studied gene. There are currently only a few studies that have investigated the function of OR8G3P in neural and psychiatric samples, and more research is needed to fully understand its role in these systems.

In conclusion, OR8G3P is a pseudogene that has been identified as a potential drug target and biomarker for a variety of neurological and psychiatric disorders. Its involvement in the regulation of sensory system function and the development of neurodegenerative diseases suggests that it may be a promising target for therapeutic intervention. Further research is needed to fully understand its role in these systems and to develop safe and effective drugs that target OR8G3P.

Protein Name: Olfactory Receptor Family 8 Subfamily G Member 3 Pseudogene

Functions: Odorant receptor

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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