Target Name: OR8U8
NCBI ID: G504189
Review Report on OR8U8 Target / Biomarker Content of Review Report on OR8U8 Target / Biomarker
OR8U8
Other Name(s): OR8U8_HUMAN | Olfactory receptor 8U8 | olfactory receptor family 8 subfamily U member 8 | Olfactory receptor, family 8, subfamily U, member 8

OR8U8: A Potential Drug Target and Biomarker for Various Diseases

OR8U8 (OR8U8_HUMAN), a protein expressed in human tissues, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. Its unique structure and expression pattern across various tissues make it an attractive target for drug development. In this article, we will discuss the OR8U8 protein, its potential drug targets, and its potential as a biomarker for various diseases.

OR8U8 Protein: Structure and Expression

OR8U8 is a 21-kDa protein that is expressed in various human tissues, including brain, heart, muscle, liver, and pancreas. It is highly expressed in the brain and has been identified as a potential drug target for various neurological disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. OR8U8 is also expressed in the liver and has been shown to be involved in the regulation of metabolism and glucose homeostasis.

OR8U8's unique structure is part of its potential as a drug target. The protein has four transmembrane domains and a cytoplasmic tail. The N-terminus of OR8U8 contains a unique farnesylated cysteine 鈥嬧?媟esidue, which is a hallmark of protein stability and may be involved in the regulation of protein stability and interactions. The C-terminus of OR8U8 contains a glycophosphorylated residue, which may be involved in protein-protein interactions and signaling.

OR8U8 has been shown to play a role in various physiological processes, including cell signaling, metabolism, and inflammation. It has been shown to be involved in the regulation of neurotransmitter release from neurons and in the modulation of glucose metabolism. Its expression has also been shown to be regulated by various factors, including DNA methylation, histone modification, and its role in infertility.

Potential Drug Targets:OR8U8 is a potential drug target for various diseases due to its unique structure and expression pattern. The N-terminus of OR8U8 has a unique farnesylated cysteine 鈥嬧?媟esidue, which is a hallmark of protein stability and may be involved in the regulation of protein stability and interactions. The C-terminus of OR8U8 contains a glycophosphorylated residue, which may be involved in protein-protein interactions and signaling.

OR8U8 has been shown to play a role in the regulation of neurotransmitter release from neurons and in the modulation of glucose metabolism. Its expression has also been shown to be regulated by various factors, including DNA methylation, histone modification, and in infertility role. Therefore, OR8U8 may be a useful drug target for various neurological disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease.

OR8U8 as a Biomarker: OR8U8 has also been shown to be a potential biomarker for various diseases. Its expression has been shown to be regulated by various factors, including DNA methylation, histone modification, and its role in infertility. Therefore, OR8U8 may be a useful biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.

Conclusion: OR8U8 is a unique protein that has been identified as a potential drug target and biomarker for various diseases. Its unique structure and expression pattern make it an attractive target for drug development. Further studies are needed to fully understand the role of OR8U8 in various diseases. physiological processes and to determine its potential as a drug target and biomarker for various diseases.

Protein Name: Olfactory Receptor Family 8 Subfamily U Member 8

Functions: Odorant receptor

The "OR8U8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR8U8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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