Target Name: SHISA6
NCBI ID: G388336
Review Report on SHISA6 Target / Biomarker Content of Review Report on SHISA6 Target / Biomarker
SHISA6
Other Name(s): OTTHUMP00000205111 | Protein shisa-6 (isoform 2) | shisa homolog 6 | FLJ45455 | SHSA6_HUMAN | OTTHUMP00000205112 | shisa family member 6 | Protein shisa-6 homolog precursor | FLJ37733 | SHISA6 variant 2 | Shisa family member 6, transcript variant 2 | Protein shisa-6 (isoform 1) | OTTHUMP00000205113 | Protein shisa-6 | Shisa family member 6, transcript variant 1 | FLJ37030 | protein shisa-6 homolog | Protein Shisa-6 | SHISA6 variant 1

SHISA6: A Potential Drug Target and Biomarker

Shisha (also known as shisha smoke) is a popular form of cannabis that has been used for centuries for medicinal and spiritual purposes. Despite its widespread use, shisha smoke has not been extensively studied for its effects on the human body. However, recent studies have identified a potential drug target and biomarker associated with shisha smoke, called SHISA6.

SHISA6: Structure and Function

SHISA6 is a non-coding RNA molecule that has been identified in the brains of mice after they have been exposed to shisha smoke. The molecule is composed of 201 amino acid residues and has been predicted to have a molecular weight of 21.9 kDa. SHISA6 is located in the hippocampus, which is responsible for memory and learning, and is involved in the formation of new memories and the regulation of anxiety and depression.

The function of SHISA6 is not yet fully understood, but its potential as a drug target and biomarker is being investigated. Studies have shown that SHISA6 is involved in the regulation of pain, anxiety, and depression, and that it may have therapeutic benefits for these conditions.

SHISA6 as a Drug Target

SHISA6 has been identified as a potential drug target for several reasons. Firstly, its location in the brain suggests that it may be involved in the development of neurological disorders. Secondly, its involvement in the regulation of pain, anxiety, and depression suggests that it may have therapeutic benefits for these conditions. Thirdly, studies have shown that SHISA6 is involved in the regulation of inflammation, which may be a key factor in the development of certain diseases.

SHISA6 has also been shown to interact with other drugs, including cannabis-derived compounds. This suggests that it may have potential as a cannabis-based treatment for certain conditions. For example, SHISA6 may have therapeutic benefits for anxiety and depression, which are common conditions associated with cannabis use.

SHISA6 as a Biomarker

SHISA6 has also been identified as a potential biomarker for several conditions. For example, studies have shown that SHISA6 levels are decreased in individuals with depression and anxiety, and that increasing SHISA6 levels may have therapeutic benefits for these conditions. Additionally, SHISA6 has been shown to be involved in the regulation of pain, which may be a key factor in the development of certain pain-related conditions.

Conclusion

In conclusion, SHISA6 is a promising drug target and biomarker associated with shisha smoke. Its location in the brain and its involvement in the regulation of pain, anxiety, and depression suggest that it may have therapeutic benefits for a variety of conditions. Further research is needed to fully understand its potential as a drug and to develop safe and effective treatments.

Protein Name: Shisa Family Member 6

Functions: Involved in maintenance of high-frequency synaptic transmission at hippocampal CA3-CA1 synapses. Regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression. May play a role in self-renewal and differentiation of spermatogonial stem cells by inhibiting canonical Wnt signaling pathway

The "SHISA6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SHISA6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SHISA7 | SHISA8 | SHISA9 | SHISAL1 | SHISAL2A | SHISAL2B | SHKBP1 | SHLD1 | SHLD2 | SHLD2P1 | SHLD2P3 | SHLD3 | SHMT1 | SHMT2 | SHOC1 | SHOC2 | Short transient receptor potential channel (TrpC) | SHOX | SHOX2 | SHPK | SHPRH | SHQ1 | SHROOM1 | SHROOM2 | SHROOM3 | SHROOM4 | SHTN1 | SI | SIAE | SIAH1 | SIAH2 | SIAH3 | Sialidase | Sialyltransferase | SIDT1 | SIDT2 | SIGIRR | SIGLEC1 | SIGLEC10 | SIGLEC11 | SIGLEC12 | SIGLEC14 | SIGLEC15 | SIGLEC16 | SIGLEC17P | SIGLEC5 | SIGLEC6 | SIGLEC7 | SIGLEC8 | SIGLEC9 | SIGLECL1 | sigma Receptor | SIGMAR1 | Signal peptidase complex | Signal recognition particle | Signal recognition particle receptor | Signal Transducers and Activators of Transcription (STAT) | SIK1 | SIK2 | SIK3 | SIKE1 | SIL1 | SILC1 | SIM1 | SIM2 | SIMC1 | SIN3 complex | SIN3A | SIN3B | SINHCAF | SIPA1 | SIPA1L1 | SIPA1L1-AS1 | SIPA1L2 | SIPA1L3 | SIRPA | SIRPAP1 | SIRPB1 | SIRPB2 | SIRPB3P | SIRPD | SIRPG | SIRPG-AS1 | SIRT1 | SIRT2 | SIRT3 | SIRT4 | SIRT5 | SIRT6 | SIRT7 | SIT1 | SIVA1 | SIX1 | SIX2 | SIX3 | SIX3-AS1 | SIX4 | SIX5 | SIX6 | SKA1