Target Name: SULT6B1
NCBI ID: G391365
Review Report on SULT6B1 Target / Biomarker Content of Review Report on SULT6B1 Target / Biomarker
SULT6B1
Other Name(s): Sulfotransferase family 6B member 1, cytosolic | sulfotransferase family 6B member 1 | Sulfotransferase family 6B member 1, transcript variant 2 | Sulfotransferase SULT6B1 | Sulfotransferase 6B1 | SULT6B1 variant 2 | ST6B1 | Sulfotransferase 6B1 (isoform 2) | sulfotransferase family, cytosolic, 6B, member 1 | Thyroxine sulfotransferase | ST6B1_HUMAN | sulfotransferase SULT6B1 | thyroxine sulfotransferase

SULT6B1: A Potential Drug Target and Biomarker

SULT6B1, also known as Sulfotransferase family 6B member 1, cytosolic, is a protein that is expressed in a variety of tissues throughout the body. It is a member of the Sulfotransferase family 6, which is a group of enzymes that are involved in the transfer of sulfur groups from reducing agents to various acceptors. SULT6B1 is primarily localized to the cytosol of cells, where it is involved in the detoxification of xenobiotics, such as drugs and other harmful substances.

SULT6B1 has been identified as a potential drug target due to its involvement in the detoxification of xenobiotics and its location in the cytosol, which is a known hub for drug transport and metabolism. Many drugs, including pharmaceuticals and environmental toxins, are taken up into cells through the endocytosis system, and then processed and eliminated within the cytosol. SULT6B1 is involved in this process, which could make it a useful target for drugs that are intended to be eliminated from the body. Additionally, SULT6B1 is also known to be involved in the detoxification of xenobiotics, which could make it a useful target for drugs that are designed to cross cell membranes and induce xenobiotics to be released from cells.

SULT6B1 is also a potential biomarker for a variety of diseases. Many diseases, including neurodegenerative disorders, are characterized by the accumulation of toxic substances in the brain. SULT6B1 is involved in the detoxification of these substances, which could make it an attractive biomarker for the detection and treatment of these diseases. Additionally, SULT6B1 is also involved in the detoxification of drugs, which could make it a useful biomarker for the detection and treatment of drug-induced neurotoxicity.

SULT6B1 is also known to play a role in the regulation of cellular processes, including cell signaling, DNA replication, and apoptosis. SULT6B1 is involved in the detoxification of intracellular reactive oxygen species (ROS), which are generated during cellular processes and can cause damage to cellular components. This could make SULT6B1 a useful target for drugs that are intended to protect against oxidative stress-induced damage.

In conclusion, SULT6B1 is a protein that is expressed in a variety of tissues throughout the body and is involved in the detoxification of xenobiotics. Its location in the cytosol and its involvement in the transfer of sulfur groups from reducing agents to various acceptors make it a potential drug target. Additionally, SULT6B1 is also a potential biomarker for a variety of diseases and is involved in the regulation of cellular processes. Further research is needed to fully understand the role of SULT6B1 in the body and its potential as a drug target and biomarker.

Protein Name: Sulfotransferase Family 6B Member 1

Functions: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of thyroxine. Involved in the metabolism of thyroxine (By similarity)

The "SULT6B1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SULT6B1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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