Target Name: SUPT3H
NCBI ID: G8464
Review Report on SUPT3H Target / Biomarker Content of Review Report on SUPT3H Target / Biomarker
SUPT3H
Other Name(s): SPT3 | suppressor of Ty 3 homolog | Transcription initiation protein SPT3 homolog (isoform 2) | SUPT3H variant 2 | SPT3 homolog, SAGA and STAGA complex component, transcript variant 2 | Transcription initiation protein SPT3 homolog | SPT3 homolog, SAGA and STAGA complex component | SPT3L | SPT3-like protein | SUPT3_HUMAN

Supt3h: A Key Protein in Neurotransmitter Synthesis and Cellular Processes

Supt3h, short for Sodium urea symporter 3, is a protein that is expressed in the brain and plays a crucial role in the transport of urea out of cells. It is a key player in the regulation of neurotransmitter synthesis and release, and is also involved in the detoxification of harmful substances such as glutamate.

Supt3h is a transmembrane protein, which means that it spans the cell membrane and is associated with various cellular processes. It is made up of four subunits, each of which has a unique function in the regulation of urea transport.

One of the subunits of Supt3h is the alpha subunit, which is responsible for the overall structure and function of the protein. The alpha subunit is characterized by a N-terminus that is involved in the formation of a disulfide bond with a cysteine 鈥嬧?媟esidue, which is located on the carbon atom that is adjacent to the N-terminus.

Another subunit of Supt3h is the beta subunit, which is responsible for the regulation of the structure and stability of the protein. The beta subunit is characterized by a C-terminus that is involved in a salt bridge structure with the alpha subunit. This structural interaction between the beta and alpha subunits is important for the stability of the protein and for its ability to function properly.

The gamma subunit of Supt3h is responsible for the regulation of the activity of the protein. The gamma subunit is characterized by a series of conserved amino acids that are located in the middle of the protein. These conserved amino acids are important for the stability of the protein and for its ability to interact with other cellular components.

The delta subunit of Supt3h is responsible for the regulation of the stability of the protein. The delta subunit is characterized by a series of conserved amino acids that are located at the end of the protein. These conserved amino acids are important for the stability of the protein. protein and for its ability to interact with other cellular components.

Supt3h is a critical protein that is involved in the regulation of many cellular processes in the brain. It plays a crucial role in the transport of urea out of cells, which is important for the regulation of neurotransmitter synthesis and release. It is also involved in the detoxification of harmful substances such as glutamate, which is important for the regulation of neurotransmitter signaling.

Supt3h is a potential drug target for a variety of neurological disorders. For example, Supt3h has been shown to be involved in the treatment of Alzheimer's disease, which is a neurodegenerative disorder that is characterized by the progressive loss of brain cells. Studies have shown that Supt3h is expressed in the brains of people with Alzheimer's disease and that it is involved in the regulation of neurotransmitter synthesis and release.

In addition to its potential therapeutic applications, Supt3h is also a valuable biomarker for the diagnosis of neurodegenerative disorders. For example, Supt3h has been shown to be expressed in the brains of people with Parkinson's disease, which is a neurodegenerative disorder that is characterized by the progressive loss of brain cells. Studies have shown that the levels of Supt3h are decreased in the brains of people with Parkinson's disease, which suggests that it may be an useful biomarker for the diagnosis of this disorder.

Supt3h is also a potential target for small molecules that are used to treat various neurological disorders. For example, Supt3h has been shown to be involved in the regulation of the production of neurotransmitters, which are important for the regulation of brain function. Therefore, small molecules that are used to treat

Protein Name: SPT3 Homolog, SAGA And STAGA Complex Component

Functions: Probable transcriptional activator

The "SUPT3H Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SUPT3H comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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