MIR136: A Potential Drug Target and Biomarker (G406927)
MIR136: A Potential Drug Target and Biomarker
MIR136 (hsa-miR-136-5p) is a non-coding RNA molecule that has been identified as a potential drug target or biomarker for various diseases, including cancer. Its unique structure and expression pattern have made it an attractive target for researchers to study, and several studies have investigated its role in various biological processes.
MIR136 is a microRNA (miRNA) that is expressed in various tissues and cells throughout the body. It is characterized by a 20-nt stem-loop region at its 3' end and a variable-length non-coding region at its 5' end. The stem-loop region is a common feature of miRNAs and is responsible for maintaining their stability and stability-dependent translation efficiency. The variable-length non-coding region is unique and has been implicated in various functions, including cell signaling, metabolism, and stress resistance.
Several studies have identified MIR136 as a potential drug target or biomarker due to its unique expression pattern and various biological functions. One study published in the journal PLoS ONE found that MIR136 was significantly downregulated in various cancer tissues compared to normal tissues, and overexpression of MIR136 was associated with cancer progression. Another study published in the journal Oncogene found that MIR136 was positively correlated with the expression of the PDGF receptor, a protein that promotes cancer cell growth and survival.
In addition to its potential as a drug target, MIR136 has also been investigated as a biomarker for various diseases. One study published in the journal Alzheimer's Dementia found that MIR136 was downregulated in the brains of individuals with Alzheimer's disease, a progressive neurodegenerative disease. Another study published in the journal Diabetes found that MIR136 was associated with increased insulin resistance and decreased sensitivity to insulin in individuals with type 2 diabetes.
The unique structure and expression pattern of MIR136 have made it an attractive target for researchers to study. Several studies have used techniques such as RNA interference, gene editing, and biochemical assays to investigate its role in various biological processes. These studies have provided valuable insights into the functions of MIR136 and its potential as a drug target or biomarker.
In conclusion, MIR136 is a non-coding RNA molecule that has been identified as a potential drug target or biomarker for various diseases. Its unique structure and expression pattern have made it an attractive target for researchers to study, and several studies have investigated its role in various biological processes. Further research is needed to fully understand the functions of MIR136 and its potential as a drug target or biomarker.
Protein Name: MicroRNA 136
The "MIR136 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR136 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
MIR137 | MIR137HG | MIR138-1 | MIR138-2 | MIR139 | MIR140 | MIR141 | MIR142 | MIR143 | MIR144 | MIR145 | MIR1468 | MIR1469 | MIR146A | MIR146B | MIR1470 | MIR1471 | MIR147A | MIR147B | MIR148A | MIR148B | MIR149 | MIR150 | MIR151A | MIR151B | MIR152 | MIR153-1 | MIR153-2 | MIR1537 | MIR1538 | MIR1539 | MIR154 | MIR155 | MIR155HG | MIR1587 | MIR15A | MIR15B | MIR16-1 | MIR16-2 | MIR17 | MIR17HG | MIR181A1 | MIR181A1HG | MIR181A2 | MIR181A2HG | MIR181B1 | MIR181B2 | MIR181C | MIR181D | MIR182 | MIR1825 | MIR1827 | MIR183 | MIR184 | MIR185 | MIR186 | MIR187 | MIR188 | MIR18A | MIR18B | MIR1908 | MIR1909 | MIR190A | MIR190B | MIR191 | MIR1910 | MIR1911 | MIR1912 | MIR1913 | MIR1914 | MIR1915 | MIR1915HG | MIR192 | MIR193A | MIR193B | MIR193BHG | MIR194-1 | MIR194-2 | MIR194-2HG | MIR195 | MIR196A1 | MIR196A2 | MIR196B | MIR197 | MIR1972-1 | MIR1972-2 | MIR1973 | MIR1976 | MIR198 | MIR199A1 | MIR199A2 | MIR199B | MIR19A | MIR19B1 | MIR19B2 | MIR200A | MIR200B | MIR200C | MIR200CHG | MIR202
