Target Name: OR14J1
NCBI ID: G442191
Review Report on OR14J1 Target / Biomarker Content of Review Report on OR14J1 Target / Biomarker
OR14J1
Other Name(s): olfactory receptor family 14 subfamily J member 1 | hs6M1-28 | Olfactory receptor OR6-25 | Olfactory receptor, family 5, subfamily U member 1 | olfactory receptor 5U1 | olfactory receptor OR6-25 | bA150A6.4 | Olfactory receptor 14J1 | OR5U1 | O14J1_HUMAN | Hs6M1-28 | OR6-25 | olfactory receptor, family 5, subfamily U member 1 | Olfactory receptor 5U1 | Olfactory receptor, family 5, subfamily U, member 1 | Olfactory receptor family 14 subfamily J member 1

OR14J1: A GPCR Mentioned as Potential Drug Target for Alzheimer's, Depression, Anxiety

OR14J1 (Olfactory Receptor Family 14 Subfamily J Member 1) is a G protein-coupled receptor (GPCR) that is expressed in the olfactory system of the human nose. It is one of the six subfamilies of the OR14J family, which is characterized by the presence of a single transmembrane domain and an extracellular loop. OR14J1 is responsible for mediating the sensitization of the olfactory system to various stimuli, including odors and chemicals.

Recent studies have identified OR14J1 as a potential drug target for the treatment of various neurological and psychiatric disorders, including Alzheimer's disease, depression, and anxiety. This is primarily due to the fact that OR14J1 is involved in the regulation of emotional and behavioral responses to environmental stimuli, and that its dysfunction has been implicated in the pathophysiology of several psychiatric conditions.

One of the key mechanisms by which OR14J1 is involved in the regulation of olfactory sensitivity is through its role in the modulation of neurotransmitter release from the olfactory neurons. OR14J1 has been shown to interact with several neurotransmitter systems, including the neurotransmitter serotonin. This includes the regulation of serotonin release by neurotransmitter release from the olfactory neurons, which is involved in the perception of odor.

Additionally, OR14J1 is involved in the regulation of neurotransmitter release from the olfactory neurons via its role in the intracellular signaling pathway of the neurotransmitter release. This pathway involves the interaction between the olfactory neurons, the neurotransmitter receptors, and the intracellular signaling pathways that regulate neurotransmitter release.

OR14J1 is also involved in the regulation of olfactory sensitivity via its role in the modulation of sensory processing. This includes the regulation of the intensity of sensory processing, as well as the modulation of the spatial distribution of sensory processing.

In addition to its role in the regulation of olfactory sensitivity, OR14J1 is also involved in the regulation of neurotransmitter release from the olfactory neurons via its role in the intracellular signaling pathway of the neurotransmitter release. This pathway involves the interaction between the olfactory neurons, the neurotransmitter receptors, and the intracellular signaling pathways that regulate neurotransmitter release.

Recent studies have identified OR14J1 as a potential drug target for the treatment of Alzheimer's disease, depression, and anxiety. This is due to the fact that OR14J1 is involved in the regulation of emotional and behavioral responses to environmental stimuli, and that its dysfunction has been implicated in the pathophysiology of these psychiatric conditions.

In conclusion, OR14J1 (Olfactory Receptor Family 14 Subfamily J Member 1) is a G protein-coupled receptor that is expressed in the olfactory system of the human nose. It is involved in the regulation of olfactory sensitivity via its role in the modulation of neurotransmitter release from the olfactory neurons, as well as its role in the regulation of sensory processing. OR14J1 is a potential drug target for the treatment of Alzheimer's disease, depression, and anxiety due to its involvement in the regulation of emotional and behavioral responses to environmental stimuli . Further research is needed to fully understand the role of OR14J1 in the regulation of olfactory sensitivity and its potential as a drug target.

Protein Name: Olfactory Receptor Family 14 Subfamily J Member 1

Functions: Odorant receptor

The "OR14J1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR14J1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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OR14L1P | OR1A1 | OR1A2 | OR1B1 | OR1C1 | OR1D2 | OR1D4 | OR1D5 | OR1E1 | OR1E2 | OR1E3 | OR1F1 | OR1F2P | OR1G1 | OR1I1 | OR1J1 | OR1J2 | OR1J4 | OR1K1 | OR1L1 | OR1L3 | OR1L4 | OR1L6 | OR1L8 | OR1M1 | OR1N1 | OR1N2 | OR1P1 | OR1Q1 | OR1S1 | OR1S2 | OR2A1 | OR2A1-AS1 | OR2A12 | OR2A14 | OR2A2 | OR2A20P | OR2A25 | OR2A4 | OR2A42 | OR2A7 | OR2A9P | OR2AE1 | OR2AG1 | OR2AG2 | OR2AJ1 | OR2AK2 | OR2AL1P | OR2AM1P | OR2AP1 | OR2AT4 | OR2B11 | OR2B2 | OR2B3 | OR2B6 | OR2C1 | OR2C3 | OR2D2 | OR2D3 | OR2F1 | OR2F2 | OR2G2 | OR2G3 | OR2G6 | OR2H1 | OR2H2 | OR2I1P | OR2J1 | OR2J2 | OR2J3 | OR2J4P | OR2K2 | OR2L13 | OR2L1P | OR2L2 | OR2L3 | OR2L5 | OR2L8 | OR2L9P | OR2M1P | OR2M2 | OR2M3 | OR2M4 | OR2M5 | OR2M7 | OR2Q1P | OR2S2 | OR2T1 | OR2T10 | OR2T11 | OR2T12 | OR2T2 | OR2T27 | OR2T29 | OR2T3 | OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5