Target Name: OR2A25
NCBI ID: G392138
Review Report on OR2A25 Target / Biomarker Content of Review Report on OR2A25 Target / Biomarker
OR2A25
Other Name(s): olfactory receptor, family 2, subfamily A, member 25 pseudogene | O2A25_HUMAN | OR2A24P | OR2A27 | olfactory receptor family 2 subfamily A member 25 | Olfactory receptor, family 2, subfamily A, member 24 pseudogene | olfactory receptor, family 2, subfamily A, member 27 | Olfactory receptor family 2 subfamily A member 25, transcript variant 1 | olfactory receptor, family 2, subfamily A, member 24 pseudogene | olfactory receptor 2A27 | Olfactory receptor 2A25 | Olfactory receptor 2A27 | Olfactory receptor, family 2, subfamily A, member 27 | Olfactory receptor, family 2, subfamily A, member 25 pseudogene | OR2A25P | OR2A25 variant 1

Potential Drug Target for Psychiatric Disorders

OR2A25, a member of the Olfactory Receptor (OR) gene family, has been identified as a potential drug target and biomarker for various psychiatric and neurological disorders. OR2A25 is a 178-amino acid transmembrane protein, which is expressed in the sweat glands, hair follicles, and sebaceous glands, and is responsible for transmitting sensory information from the skin to the brain.

The OR2A25 gene, located on chromosome 6p21.1, has been extensively studied for its role in various physiological processes, including sensory perception and regulation of skin temperature. OR2A25 has been shown to play a crucial role in the regulation of skin temperature, as increased temperature can cause it to secretify water and electrolytes, which can lead to skin dryness and itching. OR2A25 has also been shown to be involved in the regulation of pain perception and the modulation of neurotransmitter release in response to skin stimuli.

In addition to its role in skin physiology, OR2A25 has also been implicated in the pathophysiology of various psychiatric and neurological disorders. For example, OR2A25 has been shown to be reduced in individuals with major depressive disorder (MDD), and it has been suggested as a potential biomarker for this disorder. Additionally, OR2A25 has been shown to be involved in the pathophysiology of anxiety disorders, and may serve as a potential target for new therapies for this disorder.

OR2A25 has also been shown to be involved in the regulation of neurotransmitter release in response to various stimuli, including sensory inputs. For example, OR2A25 has been shown to play a role in the regulation of neurotransmitter release in response to cold temperatures, and has been shown to interact with the neurotransmitter GABA.

Given its involvement in various physiological processes and its implication in the pathophysiology of psychiatric and neurological disorders, OR2A25 has potential as a drug target and biomarker. Studies are being conducted to investigate the effects of drugs that target OR2A25 on neural function and behavior, with the goal of developing new treatments for psychiatric and neurological disorders. OR2A25 is a promising target for the development of new therapies for various psychiatric and neurological disorders, and further research is needed to fully understand its role in these conditions.

Protein Name: Olfactory Receptor Family 2 Subfamily A Member 25

Functions: Odorant receptor

The "OR2A25 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR2A25 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

OR2A4 | OR2A42 | OR2A7 | OR2A9P | OR2AE1 | OR2AG1 | OR2AG2 | OR2AJ1 | OR2AK2 | OR2AL1P | OR2AM1P | OR2AP1 | OR2AT4 | OR2B11 | OR2B2 | OR2B3 | OR2B6 | OR2C1 | OR2C3 | OR2D2 | OR2D3 | OR2F1 | OR2F2 | OR2G2 | OR2G3 | OR2G6 | OR2H1 | OR2H2 | OR2I1P | OR2J1 | OR2J2 | OR2J3 | OR2J4P | OR2K2 | OR2L13 | OR2L1P | OR2L2 | OR2L3 | OR2L5 | OR2L8 | OR2L9P | OR2M1P | OR2M2 | OR2M3 | OR2M4 | OR2M5 | OR2M7 | OR2Q1P | OR2S2 | OR2T1 | OR2T10 | OR2T11 | OR2T12 | OR2T2 | OR2T27 | OR2T29 | OR2T3 | OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6 | OR2T7 | OR2T8 | OR2U1P | OR2V1 | OR2V2 | OR2W1 | OR2W1-AS1 | OR2W3 | OR2W5P | OR2W6P | OR2Y1 | OR2Z1 | OR3A1 | OR3A2 | OR3A3 | OR3A4P | OR4A14P | OR4A15 | OR4A16 | OR4A17P | OR4A21P | OR4A47 | OR4A5 | OR4B1 | OR4C11 | OR4C12 | OR4C13 | OR4C15 | OR4C16 | OR4C1P | OR4C3 | OR4C45 | OR4C46 | OR4C5 | OR4C50P | OR4C6 | OR4D1