Target Name: OR1S2
NCBI ID: G219958
Review Report on OR1S2 Target / Biomarker Content of Review Report on OR1S2 Target / Biomarker
OR1S2
Other Name(s): olfactory receptor OR11-231 | Olfactory receptor OR11-231 | OR11-231 | Olfactory receptor 1S2 | Olfactory receptor family 1 subfamily S member 2 | OR1S2_HUMAN | olfactory receptor family 1 subfamily S member 2

OR1S2: A Potential Drug Target and Biomarker for Ovarian Cancer

Ovarian cancer is a leading cause of cancer death in women, with estimated incidence of over 21,000 new cases and 12,000 deaths in the United States alone in 2020. Despite advances in treatment, the survival rate for ovarian cancer remains relatively poor, with a five-year survival rate of only 29%. Therefore, identifying new drug targets and biomarkers for ovarian cancer is crucial for improving treatment outcomes.

One potential drug target and biomarker that has garnered significant interest in recent years is OR1S2 (olfactory receptor OR11-231). OR1S2 is a G protein-coupled receptor (GPCR) that is expressed in various tissues, including the uterus, breast tissue, and the nervous system. OR1S2 has been shown to play a role in cell signaling, and has been implicated in the development and progression of ovarian cancer.

Recent studies have suggested that OR1S2 may be a potential drug target for ovarian cancer. OR1S2 has been shown to be involved in the regulation of cell growth, apoptosis (programmed cell death), and angiogenesis (the formation of new blood vessels). In addition, OR1S2 has been shown to be involved in the development of resistance to chemotherapy in ovarian cancer.

Furthermore, OR1S2 has also been shown to be a potential biomarker for ovarian cancer. OR1S2 has been shown to be expressed in various types of ovarian cancer, including epithelial, stromal, and primordial ovarian cancer. Additionally, OR1S2 has been shown to be associated with poor prognosis in ovarian cancer patients.

In conclusion, OR1S2 is a potential drug target and biomarker for ovarian cancer. Further research is needed to fully understand its role in the development and progression of ovarian cancer, as well as its potential as a drug target. By targeting OR1S2, researchers may be able to develop new treatments for ovarian cancer that improve outcomes for women.

Protein Name: Olfactory Receptor Family 1 Subfamily S Member 2

Functions: Odorant receptor

The "OR1S2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR1S2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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OR2A1 | OR2A1-AS1 | OR2A12 | OR2A14 | OR2A2 | OR2A20P | OR2A25 | OR2A4 | OR2A42 | OR2A7 | OR2A9P | OR2AE1 | OR2AG1 | OR2AG2 | OR2AJ1 | OR2AK2 | OR2AL1P | OR2AM1P | OR2AP1 | OR2AT4 | OR2B11 | OR2B2 | OR2B3 | OR2B6 | OR2C1 | OR2C3 | OR2D2 | OR2D3 | OR2F1 | OR2F2 | OR2G2 | OR2G3 | OR2G6 | OR2H1 | OR2H2 | OR2I1P | OR2J1 | OR2J2 | OR2J3 | OR2J4P | OR2K2 | OR2L13 | OR2L1P | OR2L2 | OR2L3 | OR2L5 | OR2L8 | OR2L9P | OR2M1P | OR2M2 | OR2M3 | OR2M4 | OR2M5 | OR2M7 | OR2Q1P | OR2S2 | OR2T1 | OR2T10 | OR2T11 | OR2T12 | OR2T2 | OR2T27 | OR2T29 | OR2T3 | OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6 | OR2T7 | OR2T8 | OR2U1P | OR2V1 | OR2V2 | OR2W1 | OR2W1-AS1 | OR2W3 | OR2W5P | OR2W6P | OR2Y1 | OR2Z1 | OR3A1 | OR3A2 | OR3A3 | OR3A4P | OR4A14P | OR4A15 | OR4A16 | OR4A17P | OR4A21P | OR4A47 | OR4A5 | OR4B1 | OR4C11 | OR4C12 | OR4C13 | OR4C15 | OR4C16 | OR4C1P