OR2L2: A Potential Drug Target and Biomarker for Chronic Pain
OR2L2: A Potential Drug Target and Biomarker for Chronic Pain
OR2L2 (OR2L12) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the G protein-coupled receptor (GPCR) family, which is a large family of transmembrane proteins that play a crucial role in cellular signaling.
OR2L2 is known for its role in the regulation of pain perception and neuroinflammation. It is expressed in the central nervous system and is involved in the development and maintenance of pain states. OR2L2 has also been shown to play a key role in the regulation of inflammation, both in the central nervous system and in the immune system.
Due to its involvement in pain and inflammation, OR2L2 has been identified as a potential drug target for the treatment of a variety of neurological and psychiatric disorders. In particular, OR2L2 has been shown to be a promising candidate for the treatment of chronic pain, including chronic non-cancer pain.
One of the key challenges in the development of new pain treatments is the development of resistance to these treatments, which can limit the duration and effectiveness of the benefits. OR2L2 may be a useful biomarker for monitoring the effectiveness of pain treatments, as well as for identifying potential drug targets for chronic pain.
In addition to its potential as a drug target, OR2L2 is also a promising biomarker for the diagnosis of certain neurological disorders. For example, OR2L2 has been shown to be reduced in individuals with major depressive disorder (MDD), and may be a useful diagnostic marker for this disorder.
The study of OR2L2 is still in its early stages, and more research is needed to fully understand its role in pain and inflammation. However, the potential implications of OR2L2 as a drug target and biomarker make it an important area of research for the development of new treatments for chronic pain and other neurological disorders.
Protein Name: Olfactory Receptor Family 2 Subfamily L Member 2
Functions: Odorant receptor
The "OR2L2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR2L2 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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