OR2AG1 as A Potential Drug Target and Biomarker (G144125)

OR2AG1 as A Potential Drug Target and Biomarker

OR2AG1 (O2AG1_HUMAN), a protein that belongs to the OR2 family of transmembrane proteins, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and respiratory disorders. OR2AG1 plays a crucial role in the regulation of cell survival and metabolism, and its dysfunction has been implicated in the development and progression of numerous diseases.

OR2AG1 functions as a negative regulator of the Wnt signaling pathway, which is a well-established pathway involved in the development and maintenance of tissues and organs during embryonic development, as well as during tissue repair and regeneration. The Wnt signaling pathway is a critical regulator of cell proliferation, differentiation, and survival, and it is aberrantly activated in many diseases, including cancer, neurodegenerative diseases, and respiratory disorders.

OR2AG1 is a 21-kDa protein that consists of an N-terminus, a unique N-terminal transmembrane domain, and a C-terminus that contains a TIR domain and a conserved COOH-terminal region. The N-terminus of OR2AG1 contains a 24 amino acid residue that is involved in the formation of a N-terminal signaling domain, which is involved in the regulation of cell survival and metabolism.

The N-terminal signaling domain of OR2AG1 is composed of a unique combination of amino acids that includes a long amino acid sequence (121 amino acids) that is involved in the formation of a N-terminal tail that can interact with various signaling molecules, including TGF-β, Wnt, and FGF. This interaction between OR2AG1 and its signaling partners is critical for its function in regulating cell survival and metabolism.

OR2AG1 has been shown to play a negative role in the regulation of Wnt signaling pathway, which is a critical pathway involved in the development and maintenance of tissues and organs during embryonic development, as well as during tissue repair and regeneration. Studies have shown that OR2AG1 can inhibit the activity of the Wnt signaling pathway, including the activity of the Wnt receptor, FGF, and TGF-β.

OR2AG1 has also been shown to play a negative role in the regulation of cell survival and metabolism by regulating the expression of genes involved in cell cycle progression, apoptosis, and autophagy. In addition, OR2AG1 has been shown to play a negative role in the regulation of cell adhesion and migration, which are critical processes that are involved in the development and maintenance of tissues and organs during embryonic development, as well as during tissue repair and regeneration.

OR2AG1 has also been implicated in the development and progression of various diseases, including cancer, neurodegenerative diseases, and respiratory disorders. For example, studies have shown that OR2AG1 is involved in the regulation of the development and progression of neurobladder cancer, and that its dysfunction is associated with poor prognosis in these patients.

In addition, OR2AG1 has also been shown to be involved in the regulation of respiratory disorders, including chronic obstructive pulmonary disease (COPD) and asthma. Studies have shown that OR2AG1 is involved in the regulation of airway smooth muscle contractions, which are critical for maintaining proper lung function during inspiration and expiration. In addition, OR2AG1 has also been shown to be involved in the regulation of cytoskeletal organization and dynamics, which are critical for proper cell mechanics during respiratory movement.

In conclusion, OR2AG1 is a protein that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and respiratory disorders. Its function as a negative regulator of the Wnt signaling pathway, as well as its involvement in the regulation of cell survival and metabolism, make it an attractive target for

Protein Name: Olfactory Receptor Family 2 Subfamily AG Member 1

Functions: Odorant receptor

The "OR2AG1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR2AG1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

OR2AG2 | OR2AJ1 | OR2AK2 | OR2AL1P | OR2AM1P | OR2AP1 | OR2AT4 | OR2B11 | OR2B2 | OR2B3 | OR2B6 | OR2C1 | OR2C3 | OR2D2 | OR2D3 | OR2F1 | OR2F2 | OR2G2 | OR2G3 | OR2G6 | OR2H1 | OR2H2 | OR2I1P | OR2J1 | OR2J2 | OR2J3 | OR2J4P | OR2K2 | OR2L13 | OR2L1P | OR2L2 | OR2L3 | OR2L5 | OR2L8 | OR2L9P | OR2M1P | OR2M2 | OR2M3 | OR2M4 | OR2M5 | OR2M7 | OR2Q1P | OR2S2 | OR2T1 | OR2T10 | OR2T11 | OR2T12 | OR2T2 | OR2T27 | OR2T29 | OR2T3 | OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6 | OR2T7 | OR2T8 | OR2U1P | OR2V1 | OR2V2 | OR2W1 | OR2W1-AS1 | OR2W3 | OR2W5P | OR2W6P | OR2Y1 | OR2Z1 | OR3A1 | OR3A2 | OR3A3 | OR3A4P | OR4A14P | OR4A15 | OR4A16 | OR4A17P | OR4A21P | OR4A47 | OR4A5 | OR4B1 | OR4C11 | OR4C12 | OR4C13 | OR4C15 | OR4C16 | OR4C1P | OR4C3 | OR4C45 | OR4C46 | OR4C5 | OR4C50P | OR4C6 | OR4D1 | OR4D10 | OR4D11 | OR4D2 | OR4D5 | OR4D6 | OR4D9