OR2AL1P: A Potential Drug Target and Biomarker (G79547)
OR2AL1P: A Potential Drug Target and Biomarker
OR2AL1P, a gene that encodes for the olfactory receptor, family 2, subfamily AL, member 1 pseudogene, has been identified as a potential drug target and biomarker for various neurological and psychiatric disorders. OR2AL1P is a gene that has been implicated in the development and progression of several neurological disorders, including Alzheimer's disease, Parkinson's disease, and depression.
The olfactory receptor is a key mediator of sensory information that is responsible for detecting and recognizing different scents. OR2AL1P is a member of the OR2A family of olfactory receptors, which are known to play a crucial role in sensory function. The AL subfamily of OR2A receptors is characterized by the presence of a unique transmembrane region and a distinct N-terminus. OR2AL1P is a pseudogene that has not been shown to function as an olfactory receptor, but its sequence and expression have been identified in several brain regions and cell types.
Recent studies have suggested that OR2AL1P may be involved in the development and progression of neurological disorders. For example, overexpression of OR2AL1P has been shown to promote the development of neurofibrillary tangles and beta-amyloid plaques in animal models of Alzheimer's disease. Similarly, OR2AL1P has also been shown to be involved in the development of Parkinson's disease, with increased expression of OR2AL1P observed in the brains of patients with Parkinson's disease compared to healthy controls.
In addition to its involvement in neurological disorders, OR2AL1P has also been suggested as a potential biomarker for these disorders. The olfactory receptor is involved in the detection and recognition of different scents, and changes in the expression of OR2AL1P have been observed in the brains of patients with neurological disorders. For example, altered expression of OR2AL1P has been observed in the brains of patients with Alzheimer's disease, which may be indicative of the neurofibrillary tangles and beta-amyloid plaques that are hallmark features of this disease.
Furthermore, OR2AL1P has also been shown to be involved in the regulation of neural circuits in the brain. For example, studies have shown that OR2AL1P is involved in the regulation of dopamine release from the Striatum, a region of the brain that is involved in reward processing. This suggests that changes in the expression of OR2AL1P may be involved in the development of disorders that are characterized by abnormal dopamine release, such as Parkinson's disease.
In conclusion, OR2AL1P is a gene that has been implicated in the development and progression of several neurological disorders. Its expression and function have been studied extensively in animal models of Alzheimer's disease, Parkinson's disease, and depression. Furthermore, OR2AL1P has also been suggested as a potential biomarker for these disorders and as a drug target. Further research is needed to fully understand the role of OR2AL1P in neurological disorders and to develop effective treatments.
Protein Name: Olfactory Receptor Family 2 Subfamily AL Member 1 Pseudogene
The "OR2AL1P Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR2AL1P comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
OR2AM1P | OR2AP1 | OR2AT4 | OR2B11 | OR2B2 | OR2B3 | OR2B6 | OR2C1 | OR2C3 | OR2D2 | OR2D3 | OR2F1 | OR2F2 | OR2G2 | OR2G3 | OR2G6 | OR2H1 | OR2H2 | OR2I1P | OR2J1 | OR2J2 | OR2J3 | OR2J4P | OR2K2 | OR2L13 | OR2L1P | OR2L2 | OR2L3 | OR2L5 | OR2L8 | OR2L9P | OR2M1P | OR2M2 | OR2M3 | OR2M4 | OR2M5 | OR2M7 | OR2Q1P | OR2S2 | OR2T1 | OR2T10 | OR2T11 | OR2T12 | OR2T2 | OR2T27 | OR2T29 | OR2T3 | OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6 | OR2T7 | OR2T8 | OR2U1P | OR2V1 | OR2V2 | OR2W1 | OR2W1-AS1 | OR2W3 | OR2W5P | OR2W6P | OR2Y1 | OR2Z1 | OR3A1 | OR3A2 | OR3A3 | OR3A4P | OR4A14P | OR4A15 | OR4A16 | OR4A17P | OR4A21P | OR4A47 | OR4A5 | OR4B1 | OR4C11 | OR4C12 | OR4C13 | OR4C15 | OR4C16 | OR4C1P | OR4C3 | OR4C45 | OR4C46 | OR4C5 | OR4C50P | OR4C6 | OR4D1 | OR4D10 | OR4D11 | OR4D2 | OR4D5 | OR4D6 | OR4D9 | OR4E2 | OR4F13P | OR4F15 | OR4F16
