Heart Failure Drug Target: HSP2 (G26248)
Heart Failure Drug Target: HSP2
OR2K2 (HSHTPCRH06) is a highly expressed gene in human heart tissue that is associated with the development and progression of heart failure. The gene encodes for a protein known as heat shock protein 2 (HSP2), which is a well-known protein that is involved in a variety of cellular processes, including stress response, DNA damage repair, and cell signaling.
In recent years, researchers have become increasingly interested in the potential of HSP2 as a drug target or biomarker for the treatment of heart failure. This is because HSP2 has been shown to play a role in the regulation of cellular processes that are important for heart function, such as contractility, inflammation, and fibrosis.
One of the key reasons for the interest in HSP2 as a potential drug target is its ability to interact with a variety of signaling pathways that are involved in heart failure. For example, HSP2 has been shown to play a role in the regulation of the renin-angiotensin-aldosterone system (RAAS), a signaling pathway that is involved in the regulation of blood pressure and fluid balance.
Research has also shown that HSP2 is involved in the regulation of the myocardial fibrosis, a process that is thought to contribute to the development of heart failure. Fibrosis is the excessive accumulation of extracellular matrix (ECM) components in tissues, and it is believed to play a key role in the regulation of tissue repair and regeneration.
In addition to its role in fibrosis, HSP2 has also been shown to be involved in the regulation of cell signaling pathways that are important for heart function. For example, HSP2 has been shown to play a role in the regulation of the contractility of heart muscle, which is important for maintaining normal heart rhythm and pumping blood to the body.
Despite the potential implications of HSP2 as a drug target or biomarker for heart failure, there are currently no FDA-approved drugs that are specifically targeting HSP2. However, researchers are actively working to develop new drugs that can inhibit the activity of HSP2 and prevent or reverse the development of heart failure.
In conclusion, OR2K2 (HSHTPCRH06) is a promising drug target or biomarker for the treatment of heart failure due to its involvement in the regulation of cellular processes that are important for heart function. Further research is needed to develop new drugs that can specifically target HSP2 and prevent or reverse the development of heart failure.
Protein Name: Olfactory Receptor Family 2 Subfamily K Member 2
Functions: Odorant receptor
The "OR2K2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR2K2 comprehensively, including but not limited to:
• general information;
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• protein biological mechanisms;
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• the target screening and validation;
• expression level;
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• related combination drugs;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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OR2L13 | OR2L1P | OR2L2 | OR2L3 | OR2L5 | OR2L8 | OR2L9P | OR2M1P | OR2M2 | OR2M3 | OR2M4 | OR2M5 | OR2M7 | OR2Q1P | OR2S2 | OR2T1 | OR2T10 | OR2T11 | OR2T12 | OR2T2 | OR2T27 | OR2T29 | OR2T3 | OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6 | OR2T7 | OR2T8 | OR2U1P | OR2V1 | OR2V2 | OR2W1 | OR2W1-AS1 | OR2W3 | OR2W5P | OR2W6P | OR2Y1 | OR2Z1 | OR3A1 | OR3A2 | OR3A3 | OR3A4P | OR4A14P | OR4A15 | OR4A16 | OR4A17P | OR4A21P | OR4A47 | OR4A5 | OR4B1 | OR4C11 | OR4C12 | OR4C13 | OR4C15 | OR4C16 | OR4C1P | OR4C3 | OR4C45 | OR4C46 | OR4C5 | OR4C50P | OR4C6 | OR4D1 | OR4D10 | OR4D11 | OR4D2 | OR4D5 | OR4D6 | OR4D9 | OR4E2 | OR4F13P | OR4F15 | OR4F16 | OR4F17 | OR4F21 | OR4F29 | OR4F3 | OR4F4 | OR4F5 | OR4F6 | OR4G3P | OR4K1 | OR4K13 | OR4K14 | OR4K15 | OR4K17 | OR4K2 | OR4K5 | OR4K6P | OR4K7P | OR4L1 | OR4M1 | OR4M2 | OR4M2-OT1 | OR4N2 | OR4N3P | OR4N4
