Potential Drug Target and Biomarker for Olfactory System (G401427)
Potential Drug Target and Biomarker for Olfactory System
Olfactory receptor 2A7 (OR2A7) is a protein that is expressed in the olfactory system of the human body, which is responsible for the sense of smell. OR2A7 has been identified as a potential drug target and a biomarker for various diseases, including cancer, neurodegenerative diseases, and psychiatric disorders.
The olfactory system is a complex system of neurons and neurotransmitters that is responsible for transmitting information about the sense of smell to the brain. The sense of smell is closely linked to the brain's reward system, and the activation of OR2A7 has been linked to the perception of various smells, including sweet, sour, and umami.
OR2A7 is a transmembrane protein that is expressed in the sensory neurons of the olfactory system. It consists of a extracellular domain, a transmembrane region, and an intracellular domain. The transmembrane region of OR2A7 contains a unique cation-calcium-dependent channel that is involved in the transduction of sensory information.
OR2A7 has been shown to play a role in various physiological processes, including the sense of smell, taste, and pain. For example, OR2A7 has been shown to be involved in the perception of sweet and sour odors, and it has been shown to play a role in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.
In addition to its role in sensory perception, OR2A7 has also been shown to be involved in the regulation of pain. For example, studies have shown that OR2A7 is involved in the modulation of pain perception and that it may play a role in the development of chronic pain conditions.
OR2A7 has also been identified as a potential drug target for various diseases, including cancer, neurodegenerative diseases, and psychiatric disorders. For example, studies have shown that OR2A7 is involved in the development and progression of breast cancer, and that it may be a useful biomarker for this disease.
In addition, OR2A7 has also been shown to be involved in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. For example, studies have shown that OR2A7 is involved in the development of neurodegeneration in dopamine-dependent neurons and that it may be a useful target for the treatment of these conditions.
In addition to its potential clinical applications, OR2A7 has also been shown to be a valuable research tool for the study of olfactory system function and disease. For example, studies have shown that the expression of OR2A7 is closely correlated with the expression of other genes involved in sensory perception and that it may be a useful target for the study of these processes.
Overall, OR2A7 is a protein that has significant involvement in the sense of smell and that has been shown to play a role in various physiological processes. Its potential as a drug target and biomarker makes it an attractive target for further research and clinical development.
Protein Name: Olfactory Receptor Family 2 Subfamily A Member 7
Functions: Odorant receptor
The "OR2A7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR2A7 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
OR2A9P | OR2AE1 | OR2AG1 | OR2AG2 | OR2AJ1 | OR2AK2 | OR2AL1P | OR2AM1P | OR2AP1 | OR2AT4 | OR2B11 | OR2B2 | OR2B3 | OR2B6 | OR2C1 | OR2C3 | OR2D2 | OR2D3 | OR2F1 | OR2F2 | OR2G2 | OR2G3 | OR2G6 | OR2H1 | OR2H2 | OR2I1P | OR2J1 | OR2J2 | OR2J3 | OR2J4P | OR2K2 | OR2L13 | OR2L1P | OR2L2 | OR2L3 | OR2L5 | OR2L8 | OR2L9P | OR2M1P | OR2M2 | OR2M3 | OR2M4 | OR2M5 | OR2M7 | OR2Q1P | OR2S2 | OR2T1 | OR2T10 | OR2T11 | OR2T12 | OR2T2 | OR2T27 | OR2T29 | OR2T3 | OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6 | OR2T7 | OR2T8 | OR2U1P | OR2V1 | OR2V2 | OR2W1 | OR2W1-AS1 | OR2W3 | OR2W5P | OR2W6P | OR2Y1 | OR2Z1 | OR3A1 | OR3A2 | OR3A3 | OR3A4P | OR4A14P | OR4A15 | OR4A16 | OR4A17P | OR4A21P | OR4A47 | OR4A5 | OR4B1 | OR4C11 | OR4C12 | OR4C13 | OR4C15 | OR4C16 | OR4C1P | OR4C3 | OR4C45 | OR4C46 | OR4C5 | OR4C50P | OR4C6 | OR4D1 | OR4D10 | OR4D11 | OR4D2
