Target Name: OR2A2
NCBI ID: G442361
Review Report on OR2A2 Target / Biomarker Content of Review Report on OR2A2 Target / Biomarker
OR2A2
Other Name(s): OR2A17P | olfactory receptor OR7-11 | olfactory receptor 2A2 | Olfactory receptor, family 2, subfamily A, member 17 pseudogene | Olfactory receptor 2A17 | Olfactory receptor family 2 subfamily A member 2 | Olfactory receptor OR7-11 | olfactory receptor, family 2, subfamily A, member 2 pseudogene | OR2A2_HUMAN | OST008 | OR7-11 | OR2A2P | olfactory receptor 2A17 | olfactory receptor, family 2, subfamily A, member 17 pseudogene | Olfactory receptor, family 2, subfamily A, member 2 pseudogene | olfactory receptor family 2 subfamily A member 2 | Olfactory receptor 2A2

OR2A2: A Potential Drug Target and Biomarker for Various Diseases

OR2A2 (OR2A17P), a protein that is expressed in various tissues throughout the body, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. In this article, we will explore OR2A2, its functions, potential drug targets, and its potential as a biomarker for disease.

OR2A2 is a member of the OR2A family, which includes several related proteins that are involved in various cellular processes, including cell signaling, cell adhesion, and transcriptional regulation. OR2A2 is a 21-kDa protein that is expressed in various tissues, including brain, heart, skeletal muscles, and organs. It is highly conserved, with a calculated pI of 12.9 and a predicted localization in the endoplasmic reticulum (ER) based on its amino acid sequence.

OR2A2 functions as a negative regulator of the transcription factor NUDT, which is involved in the regulation of gene expression and cell signaling. NUDT is a critical regulator of cell proliferation and has been implicated in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders . OR2A2 functions as a negative regulator of NUDT by binding to its nuclear localization and preventing NUDT from binding to its target genes.

OR2A2 has been identified as a potential drug target for various diseases due to its involvement in NUDT regulation. One of the main reasons for its potential as a drug target is its high conservation in various species, which suggests that it is a promising target for small molecules that can inhibit its function. Several studies have shown that inhibitors of OR2A2 can suppress the growth and migration of cancer cells, indicating that it may be an effective target for cancer treatment.

In addition to its potential as a cancer drug, OR2A2 has also been identified as a potential biomarker for various diseases. Its expression is known to be elevated in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This suggests that OR2A2 may be a useful biomarker for these diseases, and that its levels can be used as a diagnostic or therapeutic target.

OR2A2 has been shown to be involved in the regulation of cellular processes that are important for disease development and progression. For example, OR2A2 has been shown to be involved in the regulation of cell adhesion, which is important for the development of cancer stem cells. In addition, OR2A2 has been shown to be involved in the regulation of cell signaling, which is important for the development and progression of neurodegenerative diseases.

In conclusion, OR2A2 is a protein that has been identified as a potential drug target and biomarker for various diseases. Its functions include regulation of NUDT, cell adhesion, and cell signaling, and its potential as a drug target and biomarker are based on its high conservation in various species and its involvement in the regulation of cellular processes that are important for disease development and progression. Further research is needed to fully understand the functions and potential of OR2A2 as a drug target and biomarker for various diseases.

Protein Name: Olfactory Receptor Family 2 Subfamily A Member 2

Functions: Odorant receptor

The "OR2A2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR2A2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

OR2A20P | OR2A25 | OR2A4 | OR2A42 | OR2A7 | OR2A9P | OR2AE1 | OR2AG1 | OR2AG2 | OR2AJ1 | OR2AK2 | OR2AL1P | OR2AM1P | OR2AP1 | OR2AT4 | OR2B11 | OR2B2 | OR2B3 | OR2B6 | OR2C1 | OR2C3 | OR2D2 | OR2D3 | OR2F1 | OR2F2 | OR2G2 | OR2G3 | OR2G6 | OR2H1 | OR2H2 | OR2I1P | OR2J1 | OR2J2 | OR2J3 | OR2J4P | OR2K2 | OR2L13 | OR2L1P | OR2L2 | OR2L3 | OR2L5 | OR2L8 | OR2L9P | OR2M1P | OR2M2 | OR2M3 | OR2M4 | OR2M5 | OR2M7 | OR2Q1P | OR2S2 | OR2T1 | OR2T10 | OR2T11 | OR2T12 | OR2T2 | OR2T27 | OR2T29 | OR2T3 | OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6 | OR2T7 | OR2T8 | OR2U1P | OR2V1 | OR2V2 | OR2W1 | OR2W1-AS1 | OR2W3 | OR2W5P | OR2W6P | OR2Y1 | OR2Z1 | OR3A1 | OR3A2 | OR3A3 | OR3A4P | OR4A14P | OR4A15 | OR4A16 | OR4A17P | OR4A21P | OR4A47 | OR4A5 | OR4B1 | OR4C11 | OR4C12 | OR4C13 | OR4C15 | OR4C16 | OR4C1P | OR4C3 | OR4C45 | OR4C46 | OR4C5 | OR4C50P