OR1J1: A GPCR Targeted for Smell and Emotional Disorders (G347168)

OR1J1: A GPCR Targeted for Smell and Emotional Disorders

Olfactory receptor OR1J1 (OR9-18) is a G protein-coupled receptor (GPCR) that is expressed in the human olfactory system, which is responsible for the sense of smell. OR1J1 is one of the many GPCRs that are known to play a role in smell perception, and it is thought to be involved in the recognition of specific scents.

Recent studies have suggested that OR1J1 may be a potential drug target or biomarker for a variety of diseases, including neurological and psychiatric disorders. This is because the Olfactory System is involved in the sense of smell, and disruptions in smell perception can be indicative of underlying neurological or psychiatric conditions.

One of the potential benefits of targeting OR1J1 is that it is a relatively small molecule, which makes it easier to manipulate with drugs. Additionally, the Olfactory System is not as complex as other sensory systems, such as the vision or auditory systems, which may make it easier to study the effects of drugs on this system.

In addition to its potential clinical applications, OR1J1 has also been studied as a potential biomarker for a variety of diseases. For example, some studies have suggested that changes in OR1J1 expression levels may be associated with certain neurological disorders, such as Alzheimer's disease and Parkinson's disease. Additionally, changes in OR1J1 expression have also been observed in conditions such as depression and anxiety, which may suggest that this receptor is involved in the regulation of emotional mood.

Another potential application of OR1J1 as a drug target is its role in the regulation of pain. Several studies have suggested that changes in OR1J1 expression levels may be associated with increased pain sensitivity, which may make this receptor a potential target for pain medications.

In conclusion, OR1J1 is a GPCR that is involved in the sense of smell and has been suggested as a potential drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of OR1J1 in the Olfactory System and its potential clinical applications.

Protein Name: Olfactory Receptor Family 1 Subfamily J Member 1

Functions: Odorant receptor

The "OR1J1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR1J1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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