OR2L3: A GPCR Responsible for The Sense of Smell (G391192)

OR2L3: A GPCR Responsible for The Sense of Smell

OR2L3 (Olfactory Receptor Family 2 Subfamily L Member 3) is a protein that is expressed in the olfactory system of the human body. It plays a crucial role in the sense of smell and is responsible for sensing odorants in the air. OR2L3 is a G protein-coupled receptor (GPCR), which means it is a transmembrane protein that is involved in cellular signaling. GPCR is a family of membrane proteins that play an important role in various cellular processes in the body, including sensory perception, neurotransmission, and signaling.

OR2L3 is a member of the Olfactory Receptor Family 2, which is a subfamily of GPCR that is responsible for mediating the sense of smell. The Olfactory Receptor Family 2 consists of four subfamilies, including OR2L1, OR2L2, OR2L3, and OR2L4. OR2L3 is the The third member of this subfamily and is responsible for mediating the sense of smell in the human body.

OR2L3 is a 144 amino acid protein that is expressed in the olfactory system of the human body. It is a GPCR that is involved in the transmembrane signaling of the olfactory system. OR2L3 is expressed in the epithelial cells of the olfactory organ and is involved in the detection of volatile organic compounds (VOCs) in the air.

OR2L3 is a GPCR that is involved in the detection of a wide variety of VOCs, including odorants, pheromones, and environmental pollutants. It is sensitive to a wide range of VOCs, including low concentrations of odorants such as linalool and toluene. OR2L3 is also sensitive to high concentrations of VOCs, such as those found in human sweat and breath.

OR2L3 is a transmembrane protein that is involved in the regulation of various cellular processes in the olfactory system. It is involved in the transduction of signals from the olfactory neurons to the central nervous system (CNS), which is responsible for processing and interpreting the sense of smell. OR2L3 is also involved in the regulation of the secretion of olfactory neurons, which is responsible for the production of the chemical signals that are responsible for the sense of smell.

OR2L3 is a potential drug target and may be a biomarker for various neurological and psychiatric disorders. For example, OR2L3 has been shown to be involved in the regulation of the sense of smell in individuals with conditions such as Alzheimer's disease, Parkinson's disease, and chronic insomnia. It is also involved in the regulation of the emotional response to smell, which may be related to the development of certain psychiatric disorders.

In conclusion, OR2L3 (Olfactory Receptor Family 2 Subfamily L Member 3) is a protein that is involved in the sense of smell and plays a crucial role in the regulation of various cellular processes in the olfactory system. It is a potential drug target and may be a biomarker for various neurological and psychiatric disorders. Further research is needed to fully understand the role of OR2L3 in the sense of smell and its potential as a drug target.

Protein Name: Olfactory Receptor Family 2 Subfamily L Member 3

Functions: Odorant receptor

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