Target Name: OPRL1
NCBI ID: G4987
Review Report on OPRL1 Target / Biomarker Content of Review Report on OPRL1 Target / Biomarker
OPRL1
Other Name(s): NOPr | N/OFQ Receptor | OP4 | Kappa-type 3 opioid receptor | opioid related nociceptin receptor 1 | Opioid related nociceptin receptor 1, transcript variant 2 | OPRL | OPRL1 variant 1 | ORL1 | OPRL1 variant 2 | ORL1 Receptor | kappa3-related opioid receptor | Nociceptin receptor (isoform 1) | N/OFQ (NOP) receptor | KOR-3 | Opioid related nociceptin receptor 1, transcript variant 1 | Orphanin FQ receptor | NOP | nociceptin/orphanin FQ receptor | opiate receptor-like 1 | orphanin FQ receptor | OPRX_HUMAN | MGC34578 | Nociceptin receptor | KOR3 | NOCIR | kappa3-Related opioid receptor | PNOCR | OOR | kappa-type 3 opioid receptor

OPRL1: A Protein Implicated in Various Physiological Processes

OPRL1 (NOPr), also known as Transthyretin, is a protein that is expressed in various tissues throughout the body. It is a potent modifier of cellular signaling pathways and has been implicated in a wide range of physiological processes, including blood clotting, inflammation, and neurodegeneration. In recent years, research has focused on understanding the potential therapeutic benefits of OPRL1 as a drug target or biomarker.

OPRL1 has been shown to play a critical role in blood clotting, which is a critical function for maintaining cardiovascular health. Clots can form in various parts of the body and can cause serious complications if not treated promptly and effectively. OPRL1 has been shown to regulate the formation of blood clots, which may have therapeutic implications for the treatment of cardiovascular disease.

In addition to its role in blood clotting, OPRL1 has also been shown to play a critical role in inflammation. Chronic inflammation can contribute to a wide range of diseases, including heart disease, cancer, and neurodegeneration. OPRL1 has also been shown to regulate the production of pro-inflammatory cytokines, which can help reduce inflammation and improve overall health.

OPRL1 has also been shown to be involved in neurodegeneration, a condition in which the brain and nervous system are damaged or dysfunctional. Neurodegeneration can be caused by a wide range of factors, including genetic mutations, infections, and environmental toxins. OPRL1 has also been shown to protect against neurodegeneration and promote neurogenesis, which may have therapeutic implications for the treatment of neurodegenerative diseases.

In addition to its role in blood clotting, OPRL1 has also been shown to play a critical role in immune function. OPRL1 is a major determinant of the immune response and has been shown to regulate the production of antibodies, which are critical for protecting the body against infections and other harmful substances.

OPRL1 has also been shown to play a critical role in regulating the production of cellulite, a common finding in obese and obese individuals. Cellulite can cause discomfort and can also lead to skin damage. OPRL1 has also been shown to regulate the production of cellulite and may have therapeutic implications for the treatment of obesity.

In conclusion, OPRL1 is a protein that has been shown to play a critical role in a wide range of physiological processes. Its potential as a drug target or biomarker makes it an attractive target for research into new therapeutic approaches. Further studies are needed to fully understand the role of OPRL1 in various biological processes and to explore its potential as a drug or biomarker.

Protein Name: Opioid Related Nociceptin Receptor 1

Functions: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin

The "OPRL1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OPRL1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

OPRM1 | OPRPN | OPTC | OPTN | OR10A2 | OR10A3 | OR10A4 | OR10A5 | OR10A6 | OR10A7 | OR10AA1P | OR10AB1P | OR10AC1 | OR10AD1 | OR10AF1P | OR10AG1 | OR10AK1P | OR10C1 | OR10D1P | OR10D3 | OR10D4P | OR10G2 | OR10G3 | OR10G4 | OR10G7 | OR10G8 | OR10G9 | OR10H1 | OR10H2 | OR10H3 | OR10H4 | OR10H5 | OR10J1 | OR10J2P | OR10J3 | OR10J5 | OR10K1 | OR10K2 | OR10P1 | OR10Q1 | OR10R2 | OR10S1 | OR10T2 | OR10V1 | OR10W1 | OR10X1 | OR10Z1 | OR11A1 | OR11G2 | OR11H1 | OR11H12 | OR11H13P | OR11H2 | OR11H5P | OR11H6 | OR11H7 | OR11J2P | OR11J5P | OR11K2P | OR11L1 | OR11M1P | OR12D2 | OR12D3 | OR13A1 | OR13C2 | OR13C3 | OR13C4 | OR13C5 | OR13C8 | OR13C9 | OR13D1 | OR13F1 | OR13G1 | OR13H1 | OR13J1 | OR13Z2P | OR14A16 | OR14A2 | OR14C36 | OR14I1 | OR14J1 | OR14L1P | OR1A1 | OR1A2 | OR1B1 | OR1C1 | OR1D2 | OR1D4 | OR1D5 | OR1E1 | OR1E2 | OR1E3 | OR1F1 | OR1F2P | OR1G1 | OR1I1 | OR1J1 | OR1J2 | OR1J4 | OR1K1