OR10A4: A Potential Drug Target and Biomarker for Olfactory Receptor function
OR10A4: A Potential Drug Target and Biomarker for Olfactory Receptor function
Olfactory receptors (ORs) are a family of transmembrane G protein-coupled receptors that play a crucial role in mediating sensory perception, including smell and taste. These receptor molecules are responsible for transmitting sensory information from the sensory system to the brain, allowing individuals to perceive and identify various scents and tastes. ORs are composed of extracellular regions that include an ion channel, a transmembrane segment, and an intracellular domain that contains a G protein-coupled receptor (GPCR) domain.
hP2, a non-coding RNA (ncRNA), has been shown to play a critical role in the regulation of olfactory receptor function. Specifically, hP2 can interact with the OR10A4 receptor, which is a known mediator of sensory perception and has been implicated in the development of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia.
The OR10A4 receptor is a GPCR that is expressed in the olfactory epithelium, which is the lining of the nasal cavity and sinuses. OR10A4 is a 17-kDa protein that consists of an N-terminus, a catalytic domain, a transmembrane segment, and a C-terminus. The OR10A4 receptor is involved in the transduction of sensory information from the olfactory epithelium to the central nervous system, allowing individuals to perceive and identify various scents and tastes.
hP2, a non-coding RNA (ncRNA), has been shown to play a critical role in the regulation of olfactory receptor function. Specifically, hP2 can interact with the OR10A4 receptor, which is a known mediator of sensory perception and has been implicated in the development of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia.
hP2 is a small non-coding RNA molecule that contains 1,184 amino acid residues. It is expressed in various tissues, including the brain, heart, and pancreas. hP2 has been shown to interact with various cellular and molecular partners, including the protein kinase A (PKA), which is a key regulator of the olfactory receptor function.
The PKA pathway is a well-established cascade of intracellular signaling pathways that are involved in the regulation of various cellular processes, including cell growth, differentiation, and survival. The PKA pathway is activated by various factors, including neurotransmitters, ion channels, and other signaling molecules.
hP2 has been shown to play a critical role in the regulation of olfactory receptor function by interacting with the PKA pathway. Specifically, hP2 can interact with the PKA protein, leading to the activation of the PKA pathway and the downstream targets of the pathway, including the Olfactory epithelium, a protein that is involved in the transduction of sensory information from the olfactory epithelium to the central nervous system.
The Olfactory is a protein that is composed of two subunits, OLF1 and OLF2. OLF1 is a 166-kDa protein that consists of an N-terminus, a transmembrane segment, and a C-terminus. OLF2 is a 22-kDa protein that consists of an N-terminus, a transmembrane segment, and a C-terminus. The Olfactory pavilion is involved in the transduction of sensory information from the olfactory epithelium to the central nervous system, allowing individuals to perceive and identify various scents and tastes.
hP2 can also interact with the
Protein Name: Olfactory Receptor Family 10 Subfamily A Member 4
Functions: Odorant receptor (Potential). May be involved in taste perception
The "OR10A4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR10A4 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
OR10A5 | OR10A6 | OR10A7 | OR10AA1P | OR10AB1P | OR10AC1 | OR10AD1 | OR10AF1P | OR10AG1 | OR10AK1P | OR10C1 | OR10D1P | OR10D3 | OR10D4P | OR10G2 | OR10G3 | OR10G4 | OR10G7 | OR10G8 | OR10G9 | OR10H1 | OR10H2 | OR10H3 | OR10H4 | OR10H5 | OR10J1 | OR10J2P | OR10J3 | OR10J5 | OR10K1 | OR10K2 | OR10P1 | OR10Q1 | OR10R2 | OR10S1 | OR10T2 | OR10V1 | OR10W1 | OR10X1 | OR10Z1 | OR11A1 | OR11G2 | OR11H1 | OR11H12 | OR11H13P | OR11H2 | OR11H5P | OR11H6 | OR11H7 | OR11J2P | OR11J5P | OR11K2P | OR11L1 | OR11M1P | OR12D2 | OR12D3 | OR13A1 | OR13C2 | OR13C3 | OR13C4 | OR13C5 | OR13C8 | OR13C9 | OR13D1 | OR13F1 | OR13G1 | OR13H1 | OR13J1 | OR13Z2P | OR14A16 | OR14A2 | OR14C36 | OR14I1 | OR14J1 | OR14L1P | OR1A1 | OR1A2 | OR1B1 | OR1C1 | OR1D2 | OR1D4 | OR1D5 | OR1E1 | OR1E2 | OR1E3 | OR1F1 | OR1F2P | OR1G1 | OR1I1 | OR1J1 | OR1J2 | OR1J4 | OR1K1 | OR1L1 | OR1L3 | OR1L4 | OR1L6 | OR1L8 | OR1M1 | OR1N1
