OR10H2: A Potential Drug Target and Biomarker for Olfactory Receptor Function

OR10H2: A Potential Drug Target and Biomarker for Olfactory Receptor Function

Olfactory receptor family 10 (OR10) is a subfamily of the T cell receptor family, which plays a crucial role in the immune system and sensory function. OR10 is composed of two transmembrane proteins, OR10H1 and OR10H2, that are involved in the detection of volatile organic compounds (VOCs) in the environment. OR10H2 is a potential drug target and biomarker due to its unique structure and function.

The OR10 receptor family consists of four members: OR10A, OR10B, OR10C, and OR10D. OR10A and OR10B are involved in the detection of methane, a potent greenhouse gas, while OR10C and OR10D are involved in the detection of VOCs, including volatile sulfur compounds (VSCs) and volatile nitrogen compounds (VNCs). OR10H2 is the most well-studied member of the OR10 family, and its function is essential for the survival of the organism.

OR10H2 is a 120-kDa transmembrane protein that consists of a catalytic region, a cytoplasmic region, and an extracellular region. The catalytic region contains a N-terminal transmembrane domain, a signal- transduction domain, and a C-terminal protein-coding region . The cytoplasmic region contains a unique structural feature called a variable region, which is involved in the recognition of different VOCs. The extracellular region contains a N-terminal transmembrane domain, a C-terminal protein-coding region, and a variable region.

OR10H2 is involved in the detection of a wide range of VOCs, including VSCs and VNCs, which are volatile compounds that are generated by cellular processes. These compounds are typically detected by the nose and are associated with the sense of smell. OR10H2 plays a crucial role in the regulation of the olfactory system, as it is involved in the detection and recognition of VOCs that are essential for the survival of the organism.

OR10H2 has been shown to be involved in a variety of cellular processes, including cell survival, growth, and differentiation. For example, studies have shown that OR10H2 plays a role in the regulation of cell proliferation in the olfactory system. OR10H2 has been shown to be involved in the regulation of the cell cycle, as it has been shown to promote the G1/S transition and the G0/G1 transition. OR10H2 has also been shown to be involved in the regulation of cell apoptosis, as it has been shown to promote the cleavage of Bcl-2 and to inhibit the cleavage of caspase-3.

OR10H2 has also been shown to be involved in the regulation of the cytoskeleton. OR10H2 has also been shown to be involved in the regulation of actin dynamics and in the organization of the cytoskeleton. of cell adhesion, as it has been shown to be involved in the regulation of tight junction formation.

In addition to its role in the regulation of cellular processes, OR10H2 has also been shown to be involved in the regulation of the olfactory system. OR10H2 has been shown to be involved in the development and maintenance of the olfactory system, as it has been shown to play a role in the formation of new olfactory neurons and in the regulation of the function of existing neurons. OR10H2 has also been shown to be involved in the regulation of the sensitivity of the olfactory system

Protein Name: Olfactory Receptor Family 10 Subfamily H Member 2

Functions: Odorant receptor

The "OR10H2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR10H2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

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