OPRD1: A Potential Drug Target for Pain and Anxiety (G4985)
OPRD1: A Potential Drug Target for Pain and Anxiety
OPRD1 (Opioid receptor delta 1) is a G protein-coupled receptor that is expressed in the brain and body's tissues. It is one of the most widely expressed GPRs, with higher expression levels in the brain than in other tissues. OPRD1 is involved in the modulation of pain, anxiety, and other physiological processes.
OPRD1 is a member of the G protein-coupled receptor (GPCR) family, which includes over 700 different genes in the human genome. GPCRs are involved in the regulation of a wide range of physiological processes, including sensory perception, neurotransmitter signaling, and cellular signaling.
OPRD1 is a transmembrane protein that is expressed in the brain and body's tissues. It consists of an extracellular portion, a transmembrane region, and an intracellular portion. The transmembrane region of OPRD1 contains a unique catalytic site that is involved in the regulation of GPCR signaling.
OPRD1 is involved in the modulation of pain, anxiety, and other physiological processes. It is expressed in the brain and body's tissues and is involved in the regulation of pain perception, neurotransmitter signaling, and cellular signaling. OPRD1 is also involved in the modulation of anxiety, emotion, and other physiological processes.
OPRD1 is a potential drug target (or biomarker) because of its involvement in the modulation of pain, anxiety, and other physiological processes. OPRD1 is a good candidate for development as a pain medication because of its involvement in the regulation of pain perception. OPRD1 may also be a good candidate for development as an anxiety medication because of its involvement in the regulation of anxiety and emotion.
In conclusion, OPRD1 is a G protein-coupled receptor that is involved in the modulation of pain, anxiety, and other physiological processes. It is a potential drug target (or biomarker) due to its involvement in the regulation of pain perception and anxiety. Further research is needed to fully understand the role of OPRD1 in the regulation of pain and anxiety.
Protein Name: Opioid Receptor Delta 1
Functions: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine
The "OPRD1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OPRD1 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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