PRLH: Key Regulator of Milk Production and Potential Drug Target

Target Name: PRLH

NCBI ID: G51052

PRLH

PRLH: Key Regulator of Milk Production and Potential Drug Target

PRLH (Prolactin-releasing peptide PrRP20) is a protein that is expressed in various tissues throughout the body, including the brain, pancreas, and gastrointestinal tract. It is a key regulator of milk production in breastfeeding women and has been identified as a potential drug target in the treatment of various conditions.

Prolactin (PRL) is a hormone that is produced by the pancreas and helps to stimulate milk production in breastfeeding women. It is important for the health and development of fetus and is a key factor in the success of breastfeeding. However, in some cases, an imbalance of PRL levels can occur, leading to a condition known as galactose intolerance. This is characterized by an inability to digest the sugar (lactose) in milk, leading to symptoms such as nausea, vomiting, and diarrhea.

PRLH is a protein that is released by the pancreas in response to the presence of PRL. It is a key regulator of milk production in breastfeeding women and has been shown to play a crucial role in the development and maintenance of milk production. PRLH is composed of two distinct chains, alpha- and beta-chains, and each chain has distinct functions.

The alpha-chain is the most abundant chain and is responsible for the production of proline, a key component of the extracellular matrix (ECM). The beta-chain is the less abundant chain and is responsible for the production of alanine, which is an amino acid that is involved in various cellular processes.

Recent studies have suggested that PRLH may have a role in the treatment of various conditions, including cancer, obesity, and neurodegenerative diseases. One potential mechanism by which PRLH may be involved in the treatment of cancer is its role in the regulation of cell growth and differentiation. Many studies have shown that cancer cells are able to maintain a high level of PRL production, which can help to promote their growth and survival. By targeting PRLH as a drug target, researchers may be able to develop new treatments for cancer.

Another potential mechanism by which PRLH may be involved in the treatment of obesity is its role in the regulation of energy metabolism. Many studies have shown that obese individuals have lower levels of PRLH than normal individuals, which may be a contributing factor to the development and maintenance of obesity. By targeting PRLH as a drug target, researchers may be able to develop new treatments for obesity.

PRLH has also been shown to be involved in the regulation of various physiological processes that are important for the health and development of the brain and nervous system. For example, PRLH has been shown to play a role in the regulation of neuron growth and differentiation, as well as the production of neurotransmitters such as dopamine and serotonin.

In addition to its potential role in the treatment of cancer and obesity, PRLH has also been identified as a potential biomarker for the diagnosis and monitoring of various diseases, including neurodegenerative diseases. The production of PRLH has been shown to be affected by a variety of factors, including the levels of PRL, the presence of certain bacteria, and certain dietary factors.

Research has also shown that PRLH may have a role in the regulation of milk production in breastfeeding women. Imbalances in PRL levels, such as those that occur in galactose intolerance, can lead to reduced milk production and an increase in the risk of complications such as mastitis. By targeting PRLH as a drug target, researchers may be able to develop new treatments for galactose intolerance and other conditions that are characterized by reduced milk production.

In conclusion, PRLH is a protein that is expressed in various tissues throughout the body and has

Protein Name: Prolactin Releasing Hormone

Functions: Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL

The "PRLH Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PRLH comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets