Target Name: CYB5R4
NCBI ID: G51167
Review Report on CYB5R4 Target / Biomarker Content of Review Report on CYB5R4 Target / Biomarker
CYB5R4
Other Name(s): flavohemoprotein b5+b5R | RP4-676J13.1 | NADPH cytochrome B5 oxidoreductase | b5+b5R | flavohemoprotein b5/b5R | Flavohemoprotein b5/b5R | NCB5OR | NB5R4_HUMAN | dJ676J13.1 | N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein | cytochrome b-type NAD(P)H oxidoreductase | cb5/cb5R | Cytochrome b5 reductase 4 | cytochrome b5 reductase 4

CYB5R4: A Potential Drug Target Or Biomarker for Hematopoietic System Dysfunction

CYB5R4, also known as flavohemoprotein b5+b5R, is a protein that is expressed in various tissues throughout the body. It is a key regulator of the hematopoietic system, which is responsible for the production of blood cells, and it has been identified as a potential drug target or biomarker for several diseases.

The hematopoietic system is a complex process that is responsible for the production and circulation of blood cells, including red blood cells, white blood cells, and platelets. Flavohemoprotein b5+b5R is a protein that is expressed in the bone marrow and is involved in the regulation of hematopoietic stem cell (HSC) proliferation and differentiation.

One of the key functions of CYB5R4 is its role in the regulation of HSC proliferation. HSCs are a type of stem cell that have the ability to develop into any type of blood cell. CYB5R4 has been shown to play a crucial role in the regulation of HSC proliferation by promoting the growth of HSCs and the expansion of their populations.

In addition to its role in HSC proliferation, CYB5R4 is also involved in the regulation of HSC differentiation. HSCs have the ability to differentiate into different types of blood cells, and CYB5R4 is required for the proper development and maturation of these cells.

The potential implications of CYB5R4 as a drug target or biomarker are significant. If CYB5R4 is successfully targeted by a drug, it could lead to the development of a new treatment for various diseases that are caused by the dysfunction of the hematopoietic system.

One of the key challenges in developing a new treatment for diseases caused by the dysfunction of the hematopoietic system is the development of effective targeting agents. CYB5R4 is a protein that is expressed in various tissues throughout the body, which makes it difficult to target. However, there are several research groups that are working to develop new targeting agents that can specifically target CYB5R4.

In addition to its potential as a drug target, CYB5R4 has also been identified as a potential biomarker for several diseases. For example, CYB5R4 has been shown to be elevated in the blood cells of patients with chronic myeloid leukemia, a type of cancer that is characterized by the overproduction of white blood cells.

In addition to its potential as a drug target or biomarker, CYB5R4 is also of interest to researchers because of its unique structure and biology. CYB5R4 is a protein that is composed of two interfering segments and it has a unique fold that allows it to interact with other proteins. This unique structure makes CYB5R4 a unique protein that is able to interact with other proteins in a specific way.

Overall, CYB5R4 is a protein that is expressed in various tissues throughout the body and is involved in the regulation of the hematopoietic system. Its unique structure and biology make it a potential drug target or biomarker for several diseases. Further research is needed to determine its full potential and to develop effective targeting agents that can specifically target CYB5R4.

Protein Name: Cytochrome B5 Reductase 4

Functions: NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin

The "CYB5R4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CYB5R4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CYB5RL | CYBA | CYBB | CYBC1 | CYBRD1 | CYC1 | Cyclin | Cyclin A | Cyclin B | Cyclin D | Cyclin D2-CDK4 complex | Cyclin-dependent kinase | Cyclin-dependent kinase inhibitor | Cyclooxygenase (COX) | Cyclophilins | CYCS | CYCSP25 | CYCSP34 | CYCSP38 | CYCSP51 | CYCSP52 | CYCSP53 | CYCSP55 | CYFIP1 | CYFIP2 | CYGB | CYLC1 | CYLC2 | CYLD | CYLD-AS1 | CYMP | CYP11A1 | CYP11B1 | CYP11B2 | CYP17A1 | CYP19A1 | CYP1A1 | CYP1A2 | CYP1B1 | CYP1B1-AS1 | CYP20A1 | CYP21A1P | CYP21A2 | CYP24A1 | CYP26A1 | CYP26B1 | CYP26C1 | CYP27A1 | CYP27B1 | CYP27C1 | CYP2A13 | CYP2A6 | CYP2A7 | CYP2A7P1 | CYP2B6 | CYP2B7P | CYP2C18 | CYP2C19 | CYP2C61P | CYP2C8 | CYP2C9 | CYP2D6 | CYP2D7 | CYP2D8P | CYP2E1 | CYP2F1 | CYP2F2P | CYP2G1P | CYP2J2 | CYP2R1 | CYP2S1 | CYP2T1P | CYP2U1 | CYP2U1-AS1 | CYP2W1 | CYP39A1 | CYP3A4 | CYP3A43 | CYP3A5 | CYP3A51P | CYP3A7 | CYP3A7-CYP3A51P | CYP3AP2 | CYP46A1 | CYP4A11 | CYP4A22 | CYP4B1 | CYP4F11 | CYP4F12 | CYP4F2 | CYP4F22 | CYP4F26P | CYP4F29P | CYP4F3 | CYP4F30P | CYP4F34P | CYP4F35P | CYP4F59P | CYP4F62P | CYP4F8