CYLC2: A Potential Drug Target and Biomarker (G1539)

Target Name: CYLC2

NCBI ID: G1539

CYLC2

CYLC2: A Potential Drug Target and Biomarker

Cylicin-2 (CYLC2) is a protein that is expressed in various tissues of the body, including the brain, lungs, heart, and kidneys. Its primary function is to regulate the balance of fluids in the body, which is essential for maintaining the health and proper functioning of various organs and systems.

CYLC2 has been identified as a potential drug target and biomarker due to its unique structure and its involvement in several physiological processes. One of the most significant features of CYLC2 is its ability to interact with various signaling molecules, including G protein-coupled receptors (GPCRs) ) and integrins. This interactivity makes CYLC2 a promising target for small molecules that can modulate its activity and potentially affect the behavior of other proteins.

In addition to its potential as a drug target, CYLC2 has also been shown to be a potential biomarker for several diseases, including heart failure, Chronic obstructive pulmonary disease (COPD), and neurodegenerative diseases. The identification of CYLC2 as a biomarker for these diseases makes it an attractive target for diagnostic tools and therapies that can improve treatment outcomes.

The structure of CYLC2 is unique, as it consists of a combination of cytoplasmic and extracellular domains. The cytoplasmic domain is responsible for the protein's stability and localization in the cytoplasm, while the extracellular domain is involved in its interactions with other proteins and signaling molecules.

The cytoplasmic domain of CYLC2 is characterized by a unique arrangement of 12 transmembrane domains. This arrangement is highly conserved across various species, including humans, and suggests that CYLC2 has a ancient evolutionary origin. The transmembrane domains are involved in the regulation of the protein's stability and localization in the cytoplasm, as well as its interactions with other proteins and signaling molecules.

The extracellular domain of CYLC2 is characterized by a series of unique structural features. The first extracellular domain is a 尾-sheet that is involved in the formation of a disulfide bond with the second transmembrane domain. This 尾-sheet is followed by a number of unique structural features, including a 纬-helix and a 未-sheet that are involved in the regulation of the protein's stability.

The second extracellular domain of CYLC2 is characterized by a unique arrangement of 12 transmembrane domains. This arrangement is highly conserved across various species, including humans, and suggests that CYLC2 has an ancient evolutionary origin. The transmembrane domains are involved in the regulation of the protein's stability and localization in the cytoplasm, as well as its interactions with other proteins and signaling molecules.

The unique structure of CYLC2 has led to its identification as a potential drug target and biomarker. The regulation of the balance of fluids in the body is essential for maintaining the health and proper functioning of various organs and systems, and the dysfunction of this regulation has has been implicated in the development of several diseases. The identification of CYLC2 as a potential drug target makes it an attractive target for small molecules that can modulate its activity and potentially affect the behavior of other proteins.

In addition to its potential as a drug target, CYLC2 has also been shown to be a potential biomarker for several diseases. The identification of CYLC2 as a biomarker for these diseases makes it an attractive target for diagnostic tools and therapies that can improve treatment outcomes. For example, the dysfunction of CYLC2 regulation has been implicated in the development of heart failure, Chronic obstructive pulmonary disease (COPD), and neurodegenerative diseases. The identification of CYLC2 as a potential biomarker for these diseases makes it an attractive target for therapies that can improve treatment outcomes.

In conclusion, CYLC2 is a protein that has unique structure and is involved in the regulation of the balance of fluids in the body. Its identification as a potential drug target and biomarker makes it an attractive target for small molecules that can modulate its activity and potentially affect the behavior of other proteins. Further research is needed to fully understand the function

Protein Name: Cylicin 2

Functions: Possible architectural role during spermatogenesis. May be involved in spermatid differentiation

The "CYLC2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CYLC2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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