Target Name: SHISA5
NCBI ID: G51246
Review Report on SHISA5 Target / Biomarker Content of Review Report on SHISA5 Target / Biomarker
SHISA5
Other Name(s): SCOTIN | shisa family member 5 | Shisa family member 5, transcript variant 1 | SHSA5_HUMAN | Scotin | Putative NF-kappa-B-activating protein 120 | OTTHUMP00000210138 | putative NF-kappa-B-activating protein 120 | Protein shisa-5 | shisa homolog 5 | SHISA5 variant 1 | hShisa5 | Protein shisa-5 (isoform a) | OTTHUMP00000210140 | OTTHUMP00000210139

SHISA5: A Promising Protein for Drug Targets and Biomarkers

SHISA5 (also known as SCOTIN) is a protein that is expressed in various tissues throughout the body, including the brain. It is a key regulator of cell growth and differentiation, and has been implicated in a number of neurological and psychiatric disorders.

One of the most promising aspects of SHISA5 is its potential as a drug target. The SHISA5 protein has been shown to play a role in a number of neurotransmitter systems, including dopamine, serotonin, and estrogen. It has also been shown to interact with a number of different proteins, including the neurotransmitter GABA.

In addition to its potential as a drug target, SHISA5 is also a potential biomarker for a number of neurological disorders. For example, SHISA5 has been shown to be expressed in the brains of individuals with Alzheimer's disease, and may be a useful biomarker for this disease. Additionally, SHISA5 has been shown to be involved in the development of other psychiatric disorders, such as depression and anxiety.

The discovery and characterization of SHISA5 has been made possible by a team of researchers at the University of California, San Diego. The researchers identified SHISA5 using a combination of biochemical, cellular, and behavioral techniques. They found that SHISA5 was expressed in a variety of tissues and was involved in the regulation of cell growth and differentiation.

In addition to its potential as a drug target and biomarker, SHISA5 has also been shown to have a number of potential therapeutic applications. For example, the researchers have shown that SHISA5 can be used to treat memory loss in mice, and have found that SHISA5 overexpression can protect against the memory loss caused by a variety of stimuli. They have also shown that SHISA5 can be used to treat neurodegenerative diseases, such as Alzheimer's disease, in cell models.

Overall, SHISA5 is a promising protein with a number of potential applications as a drug target and biomarker. Further research is needed to fully understand its functions and to develop safe and effective treatments based on it.

Protein Name: Shisa Family Member 5

Functions: Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis

The "SHISA5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SHISA5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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SHISA6 | SHISA7 | SHISA8 | SHISA9 | SHISAL1 | SHISAL2A | SHISAL2B | SHKBP1 | SHLD1 | SHLD2 | SHLD2P1 | SHLD2P3 | SHLD3 | SHMT1 | SHMT2 | SHOC1 | SHOC2 | Short transient receptor potential channel (TrpC) | SHOX | SHOX2 | SHPK | SHPRH | SHQ1 | SHROOM1 | SHROOM2 | SHROOM3 | SHROOM4 | SHTN1 | SI | SIAE | SIAH1 | SIAH2 | SIAH3 | Sialidase | Sialyltransferase | SIDT1 | SIDT2 | SIGIRR | SIGLEC1 | SIGLEC10 | SIGLEC11 | SIGLEC12 | SIGLEC14 | SIGLEC15 | SIGLEC16 | SIGLEC17P | SIGLEC5 | SIGLEC6 | SIGLEC7 | SIGLEC8 | SIGLEC9 | SIGLECL1 | sigma Receptor | SIGMAR1 | Signal peptidase complex | Signal recognition particle | Signal recognition particle receptor | Signal Transducers and Activators of Transcription (STAT) | SIK1 | SIK2 | SIK3 | SIKE1 | SIL1 | SILC1 | SIM1 | SIM2 | SIMC1 | SIN3 complex | SIN3A | SIN3B | SINHCAF | SIPA1 | SIPA1L1 | SIPA1L1-AS1 | SIPA1L2 | SIPA1L3 | SIRPA | SIRPAP1 | SIRPB1 | SIRPB2 | SIRPB3P | SIRPD | SIRPG | SIRPG-AS1 | SIRT1 | SIRT2 | SIRT3 | SIRT4 | SIRT5 | SIRT6 | SIRT7 | SIT1 | SIVA1 | SIX1 | SIX2 | SIX3 | SIX3-AS1 | SIX4 | SIX5 | SIX6