Target Name: ARMCX3
NCBI ID: G51566
Review Report on ARMCX3 Target / Biomarker Content of Review Report on ARMCX3 Target / Biomarker
ARMCX3
Other Name(s): ARMCX3 variant 1 | KIAA0443 | Arm protein lost in epithelial cancers, X chromosome, 3 | Protein ALEX3 | ALEX3 | ARMX3_HUMAN | DKFZp781N1954 | ARM protein lost in epithelial cancers on chromosome X 3 | GASP6 | MGC12199 | 1200004E24Rik | arm protein lost in epithelial cancers, X chromosome, 3 | Armadillo repeat-containing X-linked protein 3 | dJ545K15.2 | armadillo repeat containing X-linked 3 | Armadillo repeat containing X-linked 3, transcript variant 1 | DJ545K15.2

ARMCX3: A Potential Drug Target and Biomarker

Introduction

ARMCX3 (ARM-Chaperone Complex 3) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the ARMChaperone family, which is a group of proteins that play a critical role in protein-protein interactions and in the regulation of cellular processes. The ARMChaperone family is known to be involved in various cellular processes, including cell signaling, DNA replication, and protein folding. In recent years, researchers have become increasingly interested in the study of ARMCX3 and its potential role in disease, particularly in the context of neurodegenerative diseases. In this article, we will explore the biology and potential drug targets of ARMCX3.

The biological function

ARMCX3 is a protein that is expressed in the brain, heart, and kidneys, and it is involved in various cellular processes that are critical for maintaining cellular health and function. It is a member of the ARMChaperone family, which is a group of proteins that play a critical role in protein-protein interactions and in the regulation of cellular processes. The ARMChaperone family is known to be involved in various cellular processes, including cell signaling, DNA replication, and protein folding.

One of the key functions of ARMCX3 is its role in the regulation of protein-protein interactions. ARMCX3 is involved in the formation of the ARMChaperone complex, which is a protein-protein interaction domain that is critical for the regulation of protein function. This interaction is important for the regulation of various cellular processes, including cell signaling, DNA replication, and protein folding.

In addition to its role in protein-protein interactions, ARMCX3 is also involved in the regulation of cellular processes that are critical for maintaining cellular health and function. For example, ARMCX3 is involved in the regulation of the trafficking of proteins from the endoplasmic reticulum to the cytoplasm, which is critical for the delivery of proteins to the cell's various organelles. It is also involved in the regulation of the cytoskeleton, which is important for the structure and function of the cell.

Potential drug targets

The potential drug targets for ARMCX3 are numerous and varied. Its involvement in the regulation of protein-protein interactions and cellular processes that are critical for maintaining cellular health and function make it an attractive target for a variety of therapeutic approaches. Some potential drug targets for ARMCX3 include:

1. neurodegenerative diseases: ARMCX3 is involved in the regulation of various cellular processes that are critical for the development and progression of neurodegenerative diseases. Therefore, ARMCX3 may be an attractive target for the development of new therapies for neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease.
2. cancer: ARMCX3 is involved in the regulation of cellular processes that are critical for cancer development. Therefore, ARMCX3 may be an attractive target for the development of new therapies for cancer.
3. cardiovascular diseases: ARMCX3 is involved in the regulation of cellular processes that are critical for the development and progression of cardiovascular diseases. Therefore, ARMCX3 may be an attractive target for the development of new therapies for cardiovascular diseases.

Conclusion

In conclusion, ARMCX3 is a protein that is involved in various cellular processes that are critical for maintaining cellular health and function. Its involvement in the regulation of protein-protein interactions and the regulation of cellular processes that are critical for neurodegenerative diseases, cancer, and cardiovascular diseases make it an attractive target for the development of new therapies. Further research is needed to fully understand the biology and potential drug targets of ARMCX3.

Protein Name: Armadillo Repeat Containing X-linked 3

Functions: Regulates mitochondrial aggregation and transport in axons in living neurons. May link mitochondria to the TRAK2-kinesin motor complex via its interaction with Miro and TRAK2. Mitochondrial distribution and dynamics is regulated through ARMCX3 protein degradation, which is promoted by PCK and negatively regulated by WNT1. Enhances the SOX10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters

The "ARMCX3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ARMCX3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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